Norfenefrine hydrochloride

Cat. No.: HY-B1711A Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Norfenefrine) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Norfenefrine hydrochloride Chemical Structure

CAS No. : 4779-94-6

Size	Price	Stock
100 mg		Ask For Quote & Lead Time
250 mg		Ask For Quote & Lead Time

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This product is a controlled substance and not for sale in your territory.

Other Forms of Norfenefrine hydrochloride:

Norfenefrine Get quote
Norfenefrine (hydrochloride) (Standard) Get quote

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α adrenergic receptor β adrenergic receptor

Biological Activity
Purity & Documentation
References
Customer Review

Description

Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence^[1]^[2].

Molecular Weight

189.64

Formula

C₈H₁₂ClNO₂

CAS No.

4779-94-6

Appearance

Solid

Color

White to off-white

SMILES

OC(CN)C1=CC=CC(O)=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (263.66 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.2731 mL	26.3657 mL	52.7315 mL
5 mM	1.0546 mL	5.2731 mL	10.5463 mL
10 mM	0.5273 mL	2.6366 mL	5.2731 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (268 KB) SDS (252 KB)

COA (246 KB)

Handling Instructions (2659 KB)

References

[1]. Engler H, et al. Tracheal phenol red secretion, a new method for screening mucosecretolytic compounds. J Pharmacol Methods. 1984 Jun;11(3):151-7. [Content Brief] [Content Brief]

[2]. Jørgensen L, et al. Acute effect of norfenefrine on the urethral pressure profile in females with genuine stress incontinence. Urol Int. 1991;46(2):176-9. [Content Brief] [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	5.2731 mL	26.3657 mL	52.7315 mL	131.8287 mL
	5 mM	1.0546 mL	5.2731 mL	10.5463 mL	26.3657 mL
	10 mM	0.5273 mL	2.6366 mL	5.2731 mL	13.1829 mL
	15 mM	0.3515 mL	1.7577 mL	3.5154 mL	8.7886 mL
	20 mM	0.2637 mL	1.3183 mL	2.6366 mL	6.5914 mL
	25 mM	0.2109 mL	1.0546 mL	2.1093 mL	5.2731 mL
	30 mM	0.1758 mL	0.8789 mL	1.7577 mL	4.3943 mL
	40 mM	0.1318 mL	0.6591 mL	1.3183 mL	3.2957 mL
	50 mM	0.1055 mL	0.5273 mL	1.0546 mL	2.6366 mL
	60 mM	0.0879 mL	0.4394 mL	0.8789 mL	2.1971 mL
	80 mM	0.0659 mL	0.3296 mL	0.6591 mL	1.6479 mL
	100 mM	0.0527 mL	0.2637 mL	0.5273 mL	1.3183 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.