Norfenfluramine hydrochloride (Synonyms: (±)-Norfenfluramine hydrochloride)

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Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, formed through N-dealkylation of Fenfluramine. Norfenfluramine hydrochloride is also a potent anorexiant. Norfenfluramine hydrochloride can regulate serotonergic neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects after acute administration.

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Norfenfluramine hydrochloride Chemical Structure

CAS No. : 673-18-7

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Other Forms of Norfenfluramine hydrochloride:

(+)-Norfenfluramine hydrochloride Get quote
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Description	Norfenfluramine hydrochloride ((±)-Norfenfluramine hydrochloride) is the primary metabolite of Fenfluramine, formed through N-dealkylation of Fenfluramine. Norfenfluramine hydrochloride is also a potent anorexiant. Norfenfluramine hydrochloride can regulate serotonergic neurotransmission. In addition, Norfenfluramine hydrochloride exhibits sedative effects after acute administration^[1]^[2].
Molecular Weight	239.67
Formula	C₁₀H₁₃ClF₃N
CAS No.	673-18-7
SMILES	NC(CC1=CC=CC(C(F)(F)F)=C1)C.Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. Martin P, et al. In vitro evaluation of fenfluramine and norfenfluramine as victims of drug interactions. Pharmacol Res Perspect. 2022 Jun;10(3):e00958. [Content Brief] [2]. Goudie AJ, et al. Chronic anorexic and behavioural effects of the fenfluramine metabolite, norfenfluramine: an evaluation of its role in the actions of fenfluramine. Psychopharmacologia. 1974;38(1):67-74. [Content Brief]

Norfenfluramine hydrochloride Related Classifications

Neurological Disease

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norfenfluramine673-18-7(±)-NorfenfluramineDrug Metabolitesedative effectsFenfluraminemetaboliteanorexiantInhibitorinhibitorinhibit

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Norfenfluramine hydrochloride (Synonyms: (±)-Norfenfluramine hydrochloride)

Other Forms of Norfenfluramine hydrochloride:

Norfenfluramine hydrochloride Related Antibodies

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