2. Membrane Transporter/Ion Channel Metabolic Enzyme/Protease GPCR/G Protein Neuronal Signaling Others
  3. Drug Metabolite 5-HT Receptor Calcium Channel Isotope-Labeled Compounds
  4. Norfluoxetine-d5 hydrochloride

Norfluoxetine-d5 hydrochloride 

Cat. No.: HY-W011235S Purity: 99.57%
COA Handling Instructions

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Norfluoxetine-d5 (hydrochloride) is deuterium labeled 3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride.

For research use only. We do not sell to patients.

Norfluoxetine-d<sub>5</sub> hydrochloride Chemical Structure

Norfluoxetine-d5 hydrochloride Chemical Structure

CAS No. : 1188265-34-0

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1 mg USD 166 In-stock
5 mg USD 500 In-stock
10 mg USD 800 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Norfluoxetine-d5 hydrochloride:

Norfluoxetine-d5 hydrochloride Related Antibodies

Top Publications Citing Use of Products

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • Biological Activity

  • Purity & Documentation

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Description

Norfluoxetine-d5 (hydrochloride) is deuterium labeled 3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Norfluoxetine-d5 hydrochloride Related Antibodies
Molecular Weight

336.79

Formula

C16H12D5ClF3NO
CAS No.
Unlabeled CAS

83891-03-6
Appearance

Solid

Color

White to off-white

SMILES

FC(F)(F)C(C=C1)=CC=C1OC(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])CCN.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (371.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 125 mg/mL (371.15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9692 mL 14.8460 mL 29.6921 mL
5 mM 0.5938 mL 2.9692 mL 5.9384 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.9692 mL 14.8460 mL 29.6921 mL 74.2302 mL
5 mM 0.5938 mL 2.9692 mL 5.9384 mL 14.8460 mL
10 mM 0.2969 mL 1.4846 mL 2.9692 mL 7.4230 mL
15 mM 0.1979 mL 0.9897 mL 1.9795 mL 4.9487 mL
20 mM 0.1485 mL 0.7423 mL 1.4846 mL 3.7115 mL
25 mM 0.1188 mL 0.5938 mL 1.1877 mL 2.9692 mL
30 mM 0.0990 mL 0.4949 mL 0.9897 mL 2.4743 mL
40 mM 0.0742 mL 0.3712 mL 0.7423 mL 1.8558 mL
50 mM 0.0594 mL 0.2969 mL 0.5938 mL 1.4846 mL
60 mM 0.0495 mL 0.2474 mL 0.4949 mL 1.2372 mL
80 mM 0.0371 mL 0.1856 mL 0.3712 mL 0.9279 mL
100 mM 0.0297 mL 0.1485 mL 0.2969 mL 0.7423 mL
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Norfluoxetine-d5 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norfluoxetine-d51188265-34-0Drug Metabolite5-HT ReceptorCalcium ChannelIsotope-Labeled CompoundsSerotonin Receptor5-hydroxytryptamine ReceptorCa2+ channelsCa channelsInhibitorinhibitorinhibit

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