2. Metabolic Enzyme/Protease Others
  3. Ser/Thr Protease Others
  4. NOTA-AE105

NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NOTA-AE105 Chemical Structure

NOTA-AE105 Chemical Structure

CAS No. : 1820563-84-5

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5 mg USD 580 In-stock
10 mg USD 1150 In-stock
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Based on 1 publication(s) in Google Scholar

NOTA-AE105 Related Antibodies

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Description

NOTA-AE105 is an PET ligand of urokinase-type plasminogen activator receptor (uPAR), which can be radiolabeled by 64Cu and 68Ga. 68Ga-NOTA-AE105 and 64Cu-NOTA-AE105 shows high image contrast, resulting in clear tumor delineation[1][2].

IC50 & Target

Urokinase-type plasminogen activator receptor (uPAR)[2]
Molecular Weight

1511.68

Formula

C72H102N16O20
CAS No.
Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (55.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6615 mL 3.3076 mL 6.6152 mL
5 mM 0.1323 mL 0.6615 mL 1.3230 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6615 mL 3.3076 mL 6.6152 mL 16.5379 mL
5 mM 0.1323 mL 0.6615 mL 1.3230 mL 3.3076 mL
10 mM 0.0662 mL 0.3308 mL 0.6615 mL 1.6538 mL
15 mM 0.0441 mL 0.2205 mL 0.4410 mL 1.1025 mL
20 mM 0.0331 mL 0.1654 mL 0.3308 mL 0.8269 mL
25 mM 0.0265 mL 0.1323 mL 0.2646 mL 0.6615 mL
30 mM 0.0221 mL 0.1103 mL 0.2205 mL 0.5513 mL
40 mM 0.0165 mL 0.0827 mL 0.1654 mL 0.4134 mL
50 mM 0.0132 mL 0.0662 mL 0.1323 mL 0.3308 mL
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NOTA-AE105 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOTA-AE1051820563-84-5Ser/Thr ProteaseOthersSerine proteasesSerine endopeptidasesThreonine proteasesInhibitorinhibitorinhibit

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