2. Antibody-drug Conjugate/ADC Related
  3. Radionuclide-Drug Conjugates (RDCs)
  4. NOTA-NHS ester

NOTA-NHS ester is a molecule related to radiolabeling drugs (RDC) that can be used for fluorescent labeling and radioactive nuclide labeling applications.

For research use only. We do not sell to patients.

NOTA-NHS ester Chemical Structure

NOTA-NHS ester Chemical Structure

CAS No. : 1338231-09-6

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Based on 1 publication(s) in Google Scholar

NOTA-NHS ester Related Antibodies

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Description

NOTA-NHS ester is a molecule related to radiolabeling drugs (RDC) that can be used for fluorescent labeling and radioactive nuclide labeling applications[1][2].

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

400.38

Formula

C16H24N4O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CN1CCN(CC(ON2C(CCC2=O)=O)=O)CCN(CC(O)=O)CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (249.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4976 mL 12.4881 mL 24.9763 mL
5 mM 0.4995 mL 2.4976 mL 4.9953 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

SDS (393 KB)

COA (252 KB) HNMR (101 KB) MS (97 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4976 mL 12.4881 mL 24.9763 mL 62.4407 mL
5 mM 0.4995 mL 2.4976 mL 4.9953 mL 12.4881 mL
10 mM 0.2498 mL 1.2488 mL 2.4976 mL 6.2441 mL
15 mM 0.1665 mL 0.8325 mL 1.6651 mL 4.1627 mL
20 mM 0.1249 mL 0.6244 mL 1.2488 mL 3.1220 mL
25 mM 0.0999 mL 0.4995 mL 0.9991 mL 2.4976 mL
30 mM 0.0833 mL 0.4163 mL 0.8325 mL 2.0814 mL
40 mM 0.0624 mL 0.3122 mL 0.6244 mL 1.5610 mL
50 mM 0.0500 mL 0.2498 mL 0.4995 mL 1.2488 mL
60 mM 0.0416 mL 0.2081 mL 0.4163 mL 1.0407 mL
80 mM 0.0312 mL 0.1561 mL 0.3122 mL 0.7805 mL
100 mM 0.0250 mL 0.1249 mL 0.2498 mL 0.6244 mL
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NOTA-NHS ester Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOTA-NHS ester1338231-09-6Radionuclide-Drug Conjugates (RDCs)RDC，fluorescent labeling，radioactive nuclide labelingInhibitorinhibitorinhibit

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