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Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM.

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Nurr1 agonist 4 Chemical Structure

Nurr1 agonist 4 Chemical Structure

CAS No. : 87645-58-7

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Nurr1 agonist 4 Related Antibodies

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Description

Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM[1].

Molecular Weight

218.21

Formula

C12H10O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=COC(C2=CC=C(OC)C=C2)=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (572.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5827 mL 22.9137 mL 45.8274 mL
5 mM 0.9165 mL 4.5827 mL 9.1655 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.5827 mL 22.9137 mL 45.8274 mL 114.5685 mL
5 mM 0.9165 mL 4.5827 mL 9.1655 mL 22.9137 mL
10 mM 0.4583 mL 2.2914 mL 4.5827 mL 11.4569 mL
15 mM 0.3055 mL 1.5276 mL 3.0552 mL 7.6379 mL
20 mM 0.2291 mL 1.1457 mL 2.2914 mL 5.7284 mL
25 mM 0.1833 mL 0.9165 mL 1.8331 mL 4.5827 mL
30 mM 0.1528 mL 0.7638 mL 1.5276 mL 3.8190 mL
40 mM 0.1146 mL 0.5728 mL 1.1457 mL 2.8642 mL
50 mM 0.0917 mL 0.4583 mL 0.9165 mL 2.2914 mL
60 mM 0.0764 mL 0.3819 mL 0.7638 mL 1.9095 mL
80 mM 0.0573 mL 0.2864 mL 0.5728 mL 1.4321 mL
100 mM 0.0458 mL 0.2291 mL 0.4583 mL 1.1457 mL
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Nurr1 agonist 4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nurr1 agonist 487645-58-7OthersNurr1Inhibitorinhibitorinhibit

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