1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. O-Desmethyl quinidine

O-Desmethyl quinidine  (Synonyms: Cupreidine)

Cat. No.: HY-W037282 Purity: 99.05%
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O-Desmethyl quinidine (Cupreidine) is an orally active metabolite of Quinine (HY-D0143). O-Desmethyl quinidine reduces frequency of cramps in rats with spinal cord injury and shows low blood toxicity.

For research use only. We do not sell to patients.

O-Desmethyl quinidine Chemical Structure

O-Desmethyl quinidine Chemical Structure

CAS No. : 70877-75-7

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Description

O-Desmethyl quinidine (Cupreidine) is an orally active metabolite of Quinine (HY-D0143). O-Desmethyl quinidine reduces frequency of cramps in rats with spinal cord injury and shows low blood toxicity[1].

Molecular Weight

310.40

Formula

C19H22N2O2

CAS No.
Appearance

Solid

SMILES

O[C@@H](C1=CC=NC2=C1C=C(O)C=C2)[C@]3([H])[N@](C[C@@H]4C=C)CC[C@H]4C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (322.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2217 mL 16.1084 mL 32.2168 mL
5 mM 0.6443 mL 3.2217 mL 6.4434 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2217 mL 16.1084 mL 32.2168 mL 80.5420 mL
5 mM 0.6443 mL 3.2217 mL 6.4434 mL 16.1084 mL
10 mM 0.3222 mL 1.6108 mL 3.2217 mL 8.0542 mL
15 mM 0.2148 mL 1.0739 mL 2.1478 mL 5.3695 mL
20 mM 0.1611 mL 0.8054 mL 1.6108 mL 4.0271 mL
25 mM 0.1289 mL 0.6443 mL 1.2887 mL 3.2217 mL
30 mM 0.1074 mL 0.5369 mL 1.0739 mL 2.6847 mL
40 mM 0.0805 mL 0.4027 mL 0.8054 mL 2.0136 mL
50 mM 0.0644 mL 0.3222 mL 0.6443 mL 1.6108 mL
60 mM 0.0537 mL 0.2685 mL 0.5369 mL 1.3424 mL
80 mM 0.0403 mL 0.2014 mL 0.4027 mL 1.0068 mL
100 mM 0.0322 mL 0.1611 mL 0.3222 mL 0.8054 mL
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O-Desmethyl quinidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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O-Desmethyl quinidine
Cat. No.:
HY-W037282
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