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O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research.

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O4I4 Chemical Structure

O4I4 Chemical Structure

CAS No. : 412008-21-0

Size Price Stock Quantity
5 mg USD 85 In-stock
10 mg USD 135 In-stock
25 mg USD 285 In-stock
50 mg USD 458 In-stock
100 mg USD 700 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability. O4I4 extends lifespan in Caenorhabditis elegans and Drosophila. O4I4 can be used for regenerative medicine and rejuvenation research[1].

Molecular Weight

260.40

Formula

C15H20N2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=C(C(NC2=NC(C(C)(C)C)=CS2)=CC=C1)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (960.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8402 mL 19.2012 mL 38.4025 mL
5 mM 0.7680 mL 3.8402 mL 7.6805 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8402 mL 19.2012 mL 38.4025 mL 96.0061 mL
5 mM 0.7680 mL 3.8402 mL 7.6805 mL 19.2012 mL
10 mM 0.3840 mL 1.9201 mL 3.8402 mL 9.6006 mL
15 mM 0.2560 mL 1.2801 mL 2.5602 mL 6.4004 mL
20 mM 0.1920 mL 0.9601 mL 1.9201 mL 4.8003 mL
25 mM 0.1536 mL 0.7680 mL 1.5361 mL 3.8402 mL
30 mM 0.1280 mL 0.6400 mL 1.2801 mL 3.2002 mL
40 mM 0.0960 mL 0.4800 mL 0.9601 mL 2.4002 mL
50 mM 0.0768 mL 0.3840 mL 0.7680 mL 1.9201 mL
60 mM 0.0640 mL 0.3200 mL 0.6400 mL 1.6001 mL
80 mM 0.0480 mL 0.2400 mL 0.4800 mL 1.2001 mL
100 mM 0.0384 mL 0.1920 mL 0.3840 mL 0.9601 mL
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O4I4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

O4I4412008-21-0OthersInhibitorinhibitorinhibit

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