Obestatin(human) 

Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane^[1][2].

The primary structure of Obestatin(human) indicates that it only presented one lysine at position 10, which suggests that it cannot penetrate the cell membrane^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In adult male mice, intraperitoneal injection of Obestatin(human) suppresses food intake in a timeand dose-dependent manner^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2546.86

C₁₁₆H₁₇₆N₃₂O₃₃

1081110-72-6

Solid

White to off-white

FNAPFDVGIKLSGVQYQQHSQAL-NH2

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

• [1]. Guangcai Ren, et al. Effect of TAT-obestatin on proliferation, differentiation, apoptosis and lipolysis in 3T3-L1 preadipocytes. J Pept Sci. 2013 Nov;19(11):684-91.  [Content Brief]

  [2]. Jian V Zhang, et al. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science. 2005 Nov 11;310(5750):996-9.  [Content Brief]