2. Stem Cell/Wnt
  3. Oct3/4
  4. Oct4 inducer-1

Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time.

For research use only. We do not sell to patients.

Oct4 inducer-1 Chemical Structure

Oct4 inducer-1 Chemical Structure

CAS No. : 182564-41-6

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Based on 1 publication(s) in Google Scholar

Oct4 inducer-1 Related Antibodies

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Description

Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].

In Vitro

Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies[1].
Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Oct4 inducer-1 Related Antibodies
Molecular Weight

254.26

Formula

C15H11FN2O
CAS No.
Appearance

Solid

Color

Light brown to brown

SMILES

O=C(C1=CC=C(C=C1)F)NC2=CC=C3NC=CC3=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (983.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9330 mL 19.6649 mL 39.3298 mL
5 mM 0.7866 mL 3.9330 mL 7.8660 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9330 mL 19.6649 mL 39.3298 mL 98.3246 mL
5 mM 0.7866 mL 3.9330 mL 7.8660 mL 19.6649 mL
10 mM 0.3933 mL 1.9665 mL 3.9330 mL 9.8325 mL
15 mM 0.2622 mL 1.3110 mL 2.6220 mL 6.5550 mL
20 mM 0.1966 mL 0.9832 mL 1.9665 mL 4.9162 mL
25 mM 0.1573 mL 0.7866 mL 1.5732 mL 3.9330 mL
30 mM 0.1311 mL 0.6555 mL 1.3110 mL 3.2775 mL
40 mM 0.0983 mL 0.4916 mL 0.9832 mL 2.4581 mL
50 mM 0.0787 mL 0.3933 mL 0.7866 mL 1.9665 mL
60 mM 0.0655 mL 0.3277 mL 0.6555 mL 1.6387 mL
80 mM 0.0492 mL 0.2458 mL 0.4916 mL 1.2291 mL
100 mM 0.0393 mL 0.1966 mL 0.3933 mL 0.9832 mL
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Oct4 inducer-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oct4 inducer-1182564-41-6Oct3/4POU5F1Slc22a3Oct4-luc reporterNanog-luc reporterembryonic stem cellsinduced pluripotent stem cellsreprogrammingInhibitorinhibitorinhibit

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