Olanzapine N-oxide

Cat. No.: HY-119393 Purity: 98.02%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Olanzapine N-oxide is a compound under investigation for the metabolism of antipsychotic compounds. Olanzapine N-oxidation and N-demethylation are catalyzed by different enzymes, and its plasma concentration and clearance are not affected by a single factor, such as a specific genotype or smoking behavior.

For research use only. We do not sell to patients.

Olanzapine N-oxide Chemical Structure

CAS No. : 174794-02-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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This product is a controlled substance and not for sale in your territory.

Other Forms of Olanzapine N-oxide:

Olanzapine N-Oxide-d₃ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

328.43

Formula

C₁₇H₂₀N₄OS

CAS No.

174794-02-6

Appearance

Solid

Color

Light brown to yellow

SMILES

CC(S1)=CC2=C1NC3=CC=CC=C3N=C2N4CC[N+](C)([O-])CC4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (380.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0448 mL	15.2239 mL	30.4479 mL
5 mM	0.6090 mL	3.0448 mL	6.0896 mL
10 mM	0.3045 mL	1.5224 mL	3.0448 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.02%

Select Batch:

Data Sheet (276 KB) SDS (393 KB)

COA (257 KB) HNMR (258 KB) RP-HPLC (250 KB) LCMS (94 KB)

Handling Instructions (2659 KB)

References

[1]. Individual differences in in vitro and in vivo metabolic clearances of the antipsychotic drug olanzapine from non-smoking and smoking Japanese subjects genotyped for cytochrome P4502D6 and flavincontaining monooxygenase 3 [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0448 mL	15.2239 mL	30.4479 mL	76.1197 mL
	5 mM	0.6090 mL	3.0448 mL	6.0896 mL	15.2239 mL
	10 mM	0.3045 mL	1.5224 mL	3.0448 mL	7.6120 mL
	15 mM	0.2030 mL	1.0149 mL	2.0299 mL	5.0746 mL
	20 mM	0.1522 mL	0.7612 mL	1.5224 mL	3.8060 mL
	25 mM	0.1218 mL	0.6090 mL	1.2179 mL	3.0448 mL
	30 mM	0.1015 mL	0.5075 mL	1.0149 mL	2.5373 mL
	40 mM	0.0761 mL	0.3806 mL	0.7612 mL	1.9030 mL
	50 mM	0.0609 mL	0.3045 mL	0.6090 mL	1.5224 mL
	60 mM	0.0507 mL	0.2537 mL	0.5075 mL	1.2687 mL
	80 mM	0.0381 mL	0.1903 mL	0.3806 mL	0.9515 mL
	100 mM	0.0304 mL	0.1522 mL	0.3045 mL	0.7612 mL