2. Natural Products
  3. Plants Terpenoids Phenols
  4. Oleaceae Iridoids Monophenols
  5. Ligustrum lucidum Ait.
  6. Oleonuezhenide

Oleonuezhenide, isolated from Fructus Ligustri Lucidi, exerts neuroprotective effects.

For research use only. We do not sell to patients.

Oleonuezhenide Chemical Structure

Oleonuezhenide Chemical Structure

CAS No. : 112693-21-7

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1 mg USD 160 In-stock
5 mg USD 420 In-stock
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Based on 1 publication(s) in Google Scholar

Oleonuezhenide Related Antibodies

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Description

Oleonuezhenide, isolated from Fructus Ligustri Lucidi, exerts neuroprotective effects[1].

Molecular Weight

1073.01

Formula

C48H64O27
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]([C@@H]([C@@H](COC(C[C@H]1/C([C@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)OC=C1C(OC)=O)=C\C)=O)O3)O)[C@@H](OC(C[C@H]4/C([C@H](O[C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)O)O)O)OC=C4C(OC)=O)=C\C)=O)[C@@H]3OCCC6=CC=C(O)C=C6
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

Ethanol : ≥ 50 mg/mL (46.60 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9320 mL 4.6598 mL 9.3196 mL
5 mM 0.1864 mL 0.9320 mL 1.8639 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 1.25 mg/mL (1.16 mM); Clear solution

    This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 1.25 mg/mL (1.16 mM); Clear solution

    This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 0.9320 mL 4.6598 mL 9.3196 mL 23.2989 mL
5 mM 0.1864 mL 0.9320 mL 1.8639 mL 4.6598 mL
10 mM 0.0932 mL 0.4660 mL 0.9320 mL 2.3299 mL
15 mM 0.0621 mL 0.3107 mL 0.6213 mL 1.5533 mL
20 mM 0.0466 mL 0.2330 mL 0.4660 mL 1.1649 mL
25 mM 0.0373 mL 0.1864 mL 0.3728 mL 0.9320 mL
30 mM 0.0311 mL 0.1553 mL 0.3107 mL 0.7766 mL
40 mM 0.0233 mL 0.1165 mL 0.2330 mL 0.5825 mL
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Oleonuezhenide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oleonuezhenide112693-21-7OthersFructusLigustriLucidineuroprotectiveInhibitorinhibitorinhibit

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