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  2. Isotope-Labeled Compounds Endogenous Metabolite PPAR
  3. Oleoylethanolamide-d4

Oleoylethanolamide-d4  (Synonyms: N-Oleoylethanolamide-d4; Oleamide MEA-d4; Oleic acid monoethanolamide-d4)

Cat. No.: HY-107542S
Handling Instructions

Oleoylethanolamide-d4 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

For research use only. We do not sell to patients.

Oleoylethanolamide-d<sub>4</sub> Chemical Structure

Oleoylethanolamide-d4 Chemical Structure

CAS No. : 946524-36-3

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Solution
1 mg(3.03 mM * 1 mL in Ethanol) USD 540 In-stock
Solid
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Based on 1 publication(s) in Google Scholar

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Description

Oleoylethanolamide-d4 is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

329.55

Formula

C20H35D4NO2

CAS No.
Unlabeled CAS

111-58-0

Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCC/C=C\CCCCCCCC(NC([2H])([2H])C([2H])([2H])O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Solvent & Solubility
In Vitro: 

DMSO : 20.83 mg/mL (63.21 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0344 mL 15.1722 mL 30.3444 mL 75.8610 mL
5 mM 0.6069 mL 3.0344 mL 6.0689 mL 15.1722 mL
10 mM 0.3034 mL 1.5172 mL 3.0344 mL 7.5861 mL
15 mM 0.2023 mL 1.0115 mL 2.0230 mL 5.0574 mL
20 mM 0.1517 mL 0.7586 mL 1.5172 mL 3.7931 mL
25 mM 0.1214 mL 0.6069 mL 1.2138 mL 3.0344 mL
30 mM 0.1011 mL 0.5057 mL 1.0115 mL 2.5287 mL
40 mM 0.0759 mL 0.3793 mL 0.7586 mL 1.8965 mL
50 mM 0.0607 mL 0.3034 mL 0.6069 mL 1.5172 mL
60 mM 0.0506 mL 0.2529 mL 0.5057 mL 1.2644 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Oleoylethanolamide-d4
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