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  2. Biochemical Assay Reagents Radionuclide-Drug Conjugates (RDCs)
  3. p-SCN-Bn-NOTA trihydrochloride

p-SCN-Bn-NOTA trihydrochloride 

Cat. No.: HY-W782083 Purity: 99.62%
SDS COA Handling Instructions

p-SCN-Bn-NOTA (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. p-SCN-Bn-NOTA (trihydrochloride) can be used for conjugation of peptides and radionuclides.

For research use only. We do not sell to patients.

p-SCN-Bn-NOTA trihydrochloride Chemical Structure

p-SCN-Bn-NOTA trihydrochloride Chemical Structure

CAS No. : 1583289-85-3

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Description

p-SCN-Bn-NOTA (trihydrochloride)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. p-SCN-Bn-NOTA (trihydrochloride) can be used for conjugation of peptides and radionuclides.

IC50 & Target

RDC Bifunctional Chelator

 

Molecular Weight

559.89

Formula

C20H29Cl3N4O6S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CN1C(CC2=CC=C(N=C=S)C=C2)CN(CC(O)=O)CCN(CC(O)=O)CC1.Cl.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (223.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7861 mL 8.9303 mL 17.8607 mL
5 mM 0.3572 mL 1.7861 mL 3.5721 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7861 mL 8.9303 mL 17.8607 mL 44.6516 mL
5 mM 0.3572 mL 1.7861 mL 3.5721 mL 8.9303 mL
10 mM 0.1786 mL 0.8930 mL 1.7861 mL 4.4652 mL
15 mM 0.1191 mL 0.5954 mL 1.1907 mL 2.9768 mL
20 mM 0.0893 mL 0.4465 mL 0.8930 mL 2.2326 mL
25 mM 0.0714 mL 0.3572 mL 0.7144 mL 1.7861 mL
30 mM 0.0595 mL 0.2977 mL 0.5954 mL 1.4884 mL
40 mM 0.0447 mL 0.2233 mL 0.4465 mL 1.1163 mL
50 mM 0.0357 mL 0.1786 mL 0.3572 mL 0.8930 mL
60 mM 0.0298 mL 0.1488 mL 0.2977 mL 0.7442 mL
80 mM 0.0223 mL 0.1116 mL 0.2233 mL 0.5581 mL
100 mM 0.0179 mL 0.0893 mL 0.1786 mL 0.4465 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
p-SCN-Bn-NOTA trihydrochloride
Cat. No.:
HY-W782083
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