2. GPCR/G Protein Protein Tyrosine Kinase/RTK JAK/STAT Signaling Epigenetics Stem Cell/Wnt Immunology/Inflammation Apoptosis
  3. G Protein-coupled Receptor Kinase (GRK) JAK STAT IFNAR TNF Receptor Interleukin Related CXCR
  4. Paeoniflorin-6′-O-benzene sulfonate

Paeoniflorin-6′-O-benzene sulfonate  (Synonyms: CP-25)

Cat. No.: HY-168971
Handling Instructions Technical Support

Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model.

For research use only. We do not sell to patients.

Paeoniflorin-6′-O-benzene sulfonate Chemical Structure

Paeoniflorin-6′-O-benzene sulfonate Chemical Structure

CAS No. : 1390658-79-3

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Paeoniflorin-6′-O-benzene sulfonate Related Antibodies

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Description

Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model[1].

Molecular Weight

620.62

Formula

C29H32O13S
CAS No.
SMILES

O=C(C1=CC=CC=C1)OC[C@@]23[C@]4([C@]5(O[C@]2([H])O[C@@]([C@]3([H])C4)(C5)O)C)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)COS(=O)(C7=CC=CC=C7)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Paeoniflorin-6′-O-benzene sulfonate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Paeoniflorin-6′-O-benzene sulfonate1390658-79-3CP-25CP25CP 25G Protein-coupled Receptor Kinase (GRK)JAKSTATIFNARTNF ReceptorInterleukin RelatedCXCRJanus kinaseInterferon-α/β receptorInterferon-alpha/beta receptor Tumor Necrosis Factor ReceptorTNFRILCXC chemokine receptorsC-X-C motif chemokine receptorsHaCaTBALB/c mousepsoriasisInhibitorinhibitorinhibit

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