Pamidronate disodium pentahydrate (Standard)

Cat. No.: HY-B0730R Purity: ≥98%: Handling Instructions Technical Support

Pamidronate (disodium pentahydrate) (Standard) is the analytical standard of Pamidronate (disodium pentahydrate). This product is intended for research and analytical applications. Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.

For research use only. We do not sell to patients.

Pamidronate disodium pentahydrate (Standard) Chemical Structure

CAS No. : 109552-15-0

Size	Stock	Quantity
5 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks	Estimated Time of Arrival: December 31
10 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks	Estimated Time of Arrival: December 31
25 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks	Estimated Time of Arrival: December 31
50 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks	Estimated Time of Arrival: December 31
100 mg	Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Description	Pamidronate (disodium pentahydrate) (Standard) is the analytical standard of Pamidronate (disodium pentahydrate). This product is intended for research and analytical applications. Pamidronate disodium pentahydrate , the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.
Molecular Weight	369.11
Formula	C₃H₁₉NNa₂O₁₂P₂
CAS No.	109552-15-0
SMILES	OC(P(O)(O[Na])=O)(CCN)P(O)(O[Na])=O.O.O.O.O.O
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)