1. NF-κB Immunology/Inflammation Stem Cell/Wnt
  2. RANKL/RANK Toll-like Receptor (TLR) Wnt β-catenin
  3. Pamidronate disodium pentahydrate (Standard)

Pamidronate disodium pentahydrate (Standard) 

Cat. No.: HY-B0730R Purity: ≥98%
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Pamidronate (disodium pentahydrate) (Standard) is the analytical standard of Pamidronate (disodium pentahydrate). This product is intended for research and analytical applications. Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.

For research use only. We do not sell to patients.

Pamidronate disodium pentahydrate (Standard) Chemical Structure

Pamidronate disodium pentahydrate (Standard) Chemical Structure

CAS No. : 109552-15-0

Size Price Stock Quantity
5 mg USD 92 Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks
10 mg USD 137 Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks
25 mg USD 247 Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks
50 mg USD 371 Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks
100 mg USD 520 Get quote 5 - 7 weeks 4 - 6 weeks 4-6 weeks
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Description

Pamidronate (disodium pentahydrate) (Standard) is the analytical standard of Pamidronate (disodium pentahydrate). This product is intended for research and analytical applications. Pamidronate disodium pentahydrate, the second-generation nitrogen-containing bisphosphonate, is an inhibitor of bone loss. Pamidronate disodium pentahydrate significantly inhibits subchondral bone loss in early osteoarthritis by upregulating the expression of osteoprotegerin in cartilage and subchondral bone, and inhibiting the expression of RANKL and MMP-9 in both tissues, as well as TLR-4 in cartilage, thereby alleviating cartilage degeneration. Additionally, Pamidronate disodium pentahydrate can inhibit the signaling of Wnt and β-catenin, and is applicable for research on osteoporosis and osteosarcoma.

Molecular Weight

369.11

Formula

C3H19NNa2O12P2

CAS No.
SMILES

OC(P(O)(O[Na])=O)(CCN)P(O)(O[Na])=O.O.O.O.O.O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
Pamidronate disodium pentahydrate (Standard)
Cat. No.:
HY-B0730R
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