2. Cell Cycle/DNA Damage Epigenetics Autophagy Anti-infection Apoptosis
  3. HDAC Autophagy HIV Apoptosis
  4. Panobinostat (Standard)

Panobinostat (Standard)  (Synonyms: LBH589 (Standard); NVP-LBH589 (Standard))

Cat. No.: HY-10224R Purity: ≥98%
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Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat (HY-10224). This product is intended for research and analytical applications. Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma.

For research use only. We do not sell to patients.

Panobinostat (Standard) Chemical Structure

Panobinostat (Standard) Chemical Structure

CAS No. : 404950-80-7

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Description

Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">Panobinostat (Standard) (LBH589 (Standard)) is the analytical standard of Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">Panobinostat (Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">HY-10224). This product is intended for research and analytical applications. Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">Panobinostat is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities. Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells. Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">Panobinostat induces cell apoptosis and autophagy. Panobinostat.html" target="_blank" style="color: #6a4b92; font-weight:bold;">Panobinostat can be used for the study of refractory or relapsed multiple myeloma.

Molecular Weight

349.43

Formula

C21H23N3O2
CAS No.
SMILES

ONC(/C=C/C(C=C1)=CC=C1CNCCC2=C(C)NC3=CC=CC=C23)=O
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Panobinostat (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Panobinostat (Standard)404950-80-7LBH589 (Standard) NVP-LBH589 (Standard)HDACAutophagyHIVApoptosisHistone deacetylasesHuman immunodeficiency virusInhibitorinhibitorinhibit

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