2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. PD-89211

PD-89211 is a selective dopamine D4 receptor antagonist with a Ki value of 3.7 nM. PD-89211 reverses Quinpirole (HY-B1752A)-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM). PD-89211 regulates dopamine/norepinephrine metabolism in the hippocampus and can be used for research on central nervous system disorders such as schizophrenia.

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PD-89211 Chemical Structure

PD-89211 Chemical Structure

CAS No. : 444725-49-9

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PD-89211 Related Antibodies

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Description

PD-89211 is a selective dopamine D4 receptor antagonist with a Ki value of 3.7 nM. PD-89211 reverses Quinpirole (HY-B1752A)-induced [3H]thymidine uptake in CHOpro5 cells (IC50 = 2.1 nM). PD-89211 regulates dopamine/norepinephrine metabolism in the hippocampus and can be used for research on central nervous system disorders such as schizophrenia[1].

Molecular Weight

356.85

Formula

C19H21ClN4O
CAS No.
SMILES

OCC1=CC=C(N2CCN(CC3=NC4=CC=CC=C4N3)CC2)C=C1Cl
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Purity & Documentation
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PD-89211 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PD-89211444725-49-9PD89211PD 89211Dopamine ReceptorInhibitorinhibitorinhibit

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