2. Peptides
  3. Peptide and Derivatives
  4. Peptides for Drug Delivery
  5. Self-assembling Peptides

Self-assembling Peptides

Custom Peptide Synthesis

Self-assembling Peptides (29):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P6079A
    Ac-IHIHIYI-NH2 TFA 99.02%
    Ac-IHIHIYI-NH2 TFA is an amyloid self-assembling peptide variant that can be used as a bioactive nanomaterial with esterase activity.
    Ac-IHIHIYI-NH2 TFA
  • HY-P4147
    Ac-IHIHIQI-NH2 1582727-85-2 99.63%
    Ac-IHIHIQI-NH2 is a fibril-forming heptapeptide with high catalytic activity to laccase mimics. Ac-IHIHIQI-NH2 exhibits selectivity for hydrophobic p-nitrophenyl (ONp) ester substrates in the process of self-assembly.
    Ac-IHIHIQI-NH2
  • HY-P10294
    Oligopeptide P11-4 593266-60-5 98.02%
    Oligopeptide P11-4 is an α-peptide that can be self-assembled into β-sheet amyloids with a hydrogel appearance at low pH. Oligopeptide P11-4 can be used in biomimetic mineralization, enamel regeneration and oral care agent.
    Oligopeptide P11-4
  • HY-P2632A
    RAD16-I hydrochloride 2100275-49-6 98.88%
    RAD16-I hydrochloride, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes. RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs.
    RAD16-I hydrochloride
  • HY-P2263
    KLD-12 800379-47-9 99.91%
    KLD-12 is a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair.
    KLD-12
  • HY-P6299
    MAX8 944792-75-0
    MAX8 is a peptide made up of 20 residues that can fold and self-assemble under the influence of DMEM, forming a mechanically rigid hydrogel, this allows cells to be evenly immersed in the gel when the gelation is triggered in the presence of cells.
    MAX8
  • HY-P10699
    MAX1 487036-63-5
    MAX1 is a self-assembling peptide used to prepare hydrogels.
    MAX1
  • HY-P10706
    Ac-ILVAGK-NH2 1588764-53-7
    Ac-ILVAGK-NH2 is a self-assembling peptide that helps human H1 embryonic stem cells maintain their pluripotency.
    Ac-ILVAGK-NH2
  • HY-P2263A
    KLD-12 TFA
    KLD-12 TFA is the TFA salt form of KLD-12 (HY-P2263). KLD-12 TFA is a self a 12-residue self-assembling peptide that is used in tissue-engineering. KLD-12 TFA combined with SDF-1 self-assembled polypeptide enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs). KLD-12 TFA hydrogel can fill full-thickness osteochondral defects in situ and improve cartilage repair.
    KLD-12 TFA
  • HY-P4054
    IEIK 13 1426415-02-2
    IEIK 13 is a self-assembling peptide (SAP) sequence. IEIK 13 can be used for the research of cartilage tissue engineering
    IEIK 13
  • HY-P6079
    Ac-IHIHIYI-NH2 2156606-61-8
    Ac-IHIHIYI-NH2 is a fibrous heptapeptide that forms fibril-like structures with even higher esterase activity.
    Ac-IHIHIYI-NH2
  • HY-P10453
    Myr5A peptide
    Myr5A peptide is an acylated peptide composed of apolipoprotein A1 (ApoA1) analog peptide 5A peptide coupled to the saturated fatty acid myristate. Myr5A peptide self-assembled into lipid nanostructures can be used to encapsulate anthracycline Doxorubicin (HY-15142A) and Valrubicin (HY-13772) for compound release studies in vitro.
    Myr5A peptide
  • HY-P10659
    Self-assembling peptide pY1
    Self-assembling peptide pY1 is a peptide that assemblies around cancer cells and targets EGFR. When co-cultured with Ovalbumin (OVA), pY1 can effectively block the endocytosis of OVA.
    Self-assembling peptide pY1
  • HY-P10705
    KGFRWR
    KGFRWR is a short peptide sequence, belonging to self-assembling peptides (SAPs), which can self-assemble into functional nanostructures, typically nanofibers, under physiological conditions. KGFRWR can be used to target tumor cells and tumor vasculature, exhibiting antitumor activity.
    KGFRWR
  • HY-P10661
    L-KYFIL
    L-KYFIL is a pentapeptide that is amorphous on its own. When mixed with D-KYFIL, it transforms from fibrous hydrogels into plate-like networks, resulting in changes in mechanical properties and forming a crystalline state. The mixture can protect L-KYFIL from proteolytic degradation. L-KYFIL can be used to study stereocomplexation behavior of peptide sequences and in the development of biomaterials.
    L-KYFIL
  • HY-P10669
    NDI-Lyso 2999646-19-2
    NDI-Lyso is a lysosome-targeted anticancer agent that induces the formation of rigid long fibers in cancer cell lysosomes through an enzyme-instructed self-assembly (EISA) mechanism catalyzed by cathepsin B. This process triggers lysosomal swelling, membrane permeabilization (LMP), and membrane disruption, ultimately leading to cancer cell apoptosis via a non-classical caspase-independent pathway. NDI-Lyso exhibits significant selective anticancer activity in various cancer cell lines and drug-resistant cancer cells (IC50 ~10 μM) while showing low toxicity to normal cells (IC50 > 60 μM).
    NDI-Lyso
  • HY-P10701
    Q11 peptide 581799-39-5
    Q11 peptide is a β-sheet-forming peptide that plays an important role in self-assembly and targeted applications. As a scaffold peptide, Q11 peptide can display immunogenic epitopes and is widely used in peptide-based immune vaccine research. Additionally, Q11 peptide can be conjugated with MUC1 glycopeptides for the study of self-assembling, adjuvant-free MUC1 glycopeptide vaccines. Q11 peptide holds great potential for research in the field of cancer immunology.
    Q11 peptide
  • HY-P10703
    SAF-p2 292605-66-4
    SAF-p2 is a self-assembling fiber peptide that can form sticky-ended heterodimers by assembling with SAF-p2 (HY-P10702) through complementary amino acid sequences. These heterodimers further self-assemble into long-chain fiber structures. SAF-p2 is promising for the development of nanomaterials in the biomedical field .
    SAF-p2
  • HY-P10712
    Nap-GFFY 1242159-03-0
    Nap-GFFY, a naphthylacetic acid modifi ed tetrapeptide of GFFY, is a self-assembling fiber peptide.
    Nap-GFFY
  • HY-P10715
    Fmoc-KCRGDK
    Fmoc-KCRGDK is a self-assembling peptide that can be used to prepare hydrogels and assist in drug delivery for immune checkpoint inhibitors. Fmoc-KCRGDK can be applied in cancer immunotherapy research.
    Fmoc-KCRGDK