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  4. Permethrin-d5

Permethrin-d5  (Synonyms: NRDC-143-d5)

Cat. No.: HY-B0887S Purity: ≥98.0%
COA Handling Instructions

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Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].

For research use only. We do not sell to patients.

Permethrin-d<sub>5</sub> Chemical Structure

Permethrin-d5 Chemical Structure

CAS No. : 1794760-19-2

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1 mg USD 80 In-stock
5 mg USD 160 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Permethrin-d5:

Permethrin-d5 Related Antibodies

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Description

Permethrin-d5 (NRDC-143-d5) is the deuterium labeled Permethrin. Permethrin (NRDC-143) is an insecticide, acaricide, and insect repellent; functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Permethrin-d5 Related Antibodies
Molecular Weight

396.32

Formula

C21H15D5Cl2O3
CAS No.
Unlabeled CAS

52645-53-1
Appearance

Solid

Color

White to off-white

SMILES

C(=C(Cl)Cl)C1C(C(OCC2=CC(OC3=C(C(=C(C(=C3[2H])[2H])[2H])[2H])[2H])=CC=C2)=O)C1(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (126.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (126.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5232 mL 12.6161 mL 25.2321 mL
5 mM 0.5046 mL 2.5232 mL 5.0464 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.5232 mL 12.6161 mL 25.2321 mL 63.0803 mL
5 mM 0.5046 mL 2.5232 mL 5.0464 mL 12.6161 mL
10 mM 0.2523 mL 1.2616 mL 2.5232 mL 6.3080 mL
15 mM 0.1682 mL 0.8411 mL 1.6821 mL 4.2054 mL
20 mM 0.1262 mL 0.6308 mL 1.2616 mL 3.1540 mL
25 mM 0.1009 mL 0.5046 mL 1.0093 mL 2.5232 mL
30 mM 0.0841 mL 0.4205 mL 0.8411 mL 2.1027 mL
40 mM 0.0631 mL 0.3154 mL 0.6308 mL 1.5770 mL
50 mM 0.0505 mL 0.2523 mL 0.5046 mL 1.2616 mL
60 mM 0.0421 mL 0.2103 mL 0.4205 mL 1.0513 mL
80 mM 0.0315 mL 0.1577 mL 0.3154 mL 0.7885 mL
100 mM 0.0252 mL 0.1262 mL 0.2523 mL 0.6308 mL
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Permethrin-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Permethrin-d51794760-19-2NRDC-143-d5ParasiteInhibitorinhibitorinhibit

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