2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. Phenylarsine oxide

Phenylarsine oxide  (Synonyms: Oxophenylarsine; PhAsO; Arsenosobenzene)

Cat. No.: HY-131901 Purity: 98.65%
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Phenylarsine oxide (PAO), an inhibitor of endocytosis, inhibits PTPε with an IC50 of 18 μM. Phenylarsine oxide (PAO) inhibits oxygen consumption and decreases cellular ATP content overlap with those used to inhibit protein internalization.

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Phenylarsine oxide Chemical Structure

Phenylarsine oxide Chemical Structure

CAS No. : 637-03-6

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Phenylarsine oxide Related Antibodies

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Description

Phenylarsine oxide (PAO), an inhibitor of endocytosis, inhibits PTPε with an IC50 of 18 μM. Phenylarsine oxide (PAO) inhibits oxygen consumption and decreases cellular ATP content overlap with those used to inhibit protein internalization[1][2].

Molecular Weight

168.02

Formula

C6H5AsO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=[As]C1=CC=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 40 mg/mL (238.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.9517 mL 29.7584 mL 59.5167 mL
5 mM 1.1903 mL 5.9517 mL 11.9033 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.9517 mL 29.7584 mL 59.5167 mL 148.7918 mL
5 mM 1.1903 mL 5.9517 mL 11.9033 mL 29.7584 mL
10 mM 0.5952 mL 2.9758 mL 5.9517 mL 14.8792 mL
15 mM 0.3968 mL 1.9839 mL 3.9678 mL 9.9195 mL
20 mM 0.2976 mL 1.4879 mL 2.9758 mL 7.4396 mL
25 mM 0.2381 mL 1.1903 mL 2.3807 mL 5.9517 mL
30 mM 0.1984 mL 0.9919 mL 1.9839 mL 4.9597 mL
40 mM 0.1488 mL 0.7440 mL 1.4879 mL 3.7198 mL
50 mM 0.1190 mL 0.5952 mL 1.1903 mL 2.9758 mL
60 mM 0.0992 mL 0.4960 mL 0.9919 mL 2.4799 mL
80 mM 0.0744 mL 0.3720 mL 0.7440 mL 1.8599 mL
100 mM 0.0595 mL 0.2976 mL 0.5952 mL 1.4879 mL
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Phenylarsine oxide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phenylarsine oxide637-03-6Oxophenylarsine PhAsO ArsenosobenzenePhosphataseendocytosisPTPεasialofetuinInhibitorinhibitorinhibit

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