1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Phosphoenolpyruvic acid cyclohexylammoniu​m salt

Phosphoenolpyruvic acid cyclohexylammoniu​m salt  (Synonyms: Phosphoenolpyruvate cyclohexylammoniu​m salt)

Cat. No.: HY-W011704 Purity: ≥98.0%
Handling Instructions Technical Support

Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties.

For research use only. We do not sell to patients.

Phosphoenolpyruvic acid cyclohexylammoniu​m salt Chemical Structure

Phosphoenolpyruvic acid cyclohexylammoniu​m salt Chemical Structure

CAS No. : 10526-80-4

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Phosphoenolpyruvic acid cyclohexylammoniu​m salt

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Phosphoenolpyruvic acid (Phosphoenolpyruvate) cyclohexylammonium salt is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid cyclohexylammonium salt is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid cyclohexylammonium salt also exhibits cytoprotective and anti-oxidative properties[1].

In Vitro

Phosphoenolpyruvic acid (0.1-10 mM) cyclohexylammonium salt significantly attenuates the decrease in cell viability induced by hydrogen peroxide (H2O2) in HeLa cells in a dose-dependent manner. The H2O2-stimulated increase in intracellular reactive oxygen species is significantly reduced by Phosphoenolpyruvic acid cyclohexylammonium salt[1].
Phosphoenolpyruvic acid cyclohexylammonium salt demonstrates scavenging potential against hydroxyl radicals[1].
Phosphoenolpyruvic acid (10 mM) cyclohexylammonium salt slightly inhibits the decrease in cellular ATP content induced by H2O2, but does not show any effects at low doses (0.1 mM and 1 mM)[1].
Phosphoenolpyruvic acid (0.1-10 mM) cyclohexylammonium salt also attenuates the cell injury but not the decrease in intracellular ATP content, induced by 2-Deoxy-D-glucose (HY-13966), a glycolysis inhibitor[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

267.22

Formula

C9H18NO6P

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

NC1CCCCC1.C=C(OP(O)(O)=O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (374.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7422 mL 18.7112 mL 37.4224 mL
5 mM 0.7484 mL 3.7422 mL 7.4845 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7422 mL 18.7112 mL 37.4223 mL 93.5559 mL
5 mM 0.7484 mL 3.7422 mL 7.4845 mL 18.7112 mL
10 mM 0.3742 mL 1.8711 mL 3.7422 mL 9.3556 mL
15 mM 0.2495 mL 1.2474 mL 2.4948 mL 6.2371 mL
20 mM 0.1871 mL 0.9356 mL 1.8711 mL 4.6778 mL
25 mM 0.1497 mL 0.7484 mL 1.4969 mL 3.7422 mL
30 mM 0.1247 mL 0.6237 mL 1.2474 mL 3.1185 mL
40 mM 0.0936 mL 0.4678 mL 0.9356 mL 2.3389 mL
50 mM 0.0748 mL 0.3742 mL 0.7484 mL 1.8711 mL
60 mM 0.0624 mL 0.3119 mL 0.6237 mL 1.5593 mL
80 mM 0.0468 mL 0.2339 mL 0.4678 mL 1.1694 mL
100 mM 0.0374 mL 0.1871 mL 0.3742 mL 0.9356 mL
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Phosphoenolpyruvic acid cyclohexylammoniu​m salt Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phosphoenolpyruvic acid cyclohexylammoniu​m salt
Cat. No.:
HY-W011704
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