1. Anti-infection Metabolic Enzyme/Protease
  2. Orthopoxvirus Endogenous Metabolite
  3. Phosphonoacetic acid

Phosphonoacetic acid is an endogenous metabolite. Phosphonoacetic acid also has anti-orthopoxvirus activity.

For research use only. We do not sell to patients.

Phosphonoacetic acid Chemical Structure

Phosphonoacetic acid Chemical Structure

CAS No. : 4408-78-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
100 mg USD 50 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

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Description

Phosphonoacetic acid is an endogenous metabolite. Phosphonoacetic acid also has anti-orthopoxvirus activity[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

140.03

Formula

C2H5O5P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CP(O)(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 260 mg/mL (1856.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.1413 mL 35.7066 mL 71.4133 mL
5 mM 1.4283 mL 7.1413 mL 14.2827 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (714.13 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.1413 mL 35.7066 mL 71.4133 mL 178.5332 mL
5 mM 1.4283 mL 7.1413 mL 14.2827 mL 35.7066 mL
10 mM 0.7141 mL 3.5707 mL 7.1413 mL 17.8533 mL
15 mM 0.4761 mL 2.3804 mL 4.7609 mL 11.9022 mL
20 mM 0.3571 mL 1.7853 mL 3.5707 mL 8.9267 mL
25 mM 0.2857 mL 1.4283 mL 2.8565 mL 7.1413 mL
30 mM 0.2380 mL 1.1902 mL 2.3804 mL 5.9511 mL
40 mM 0.1785 mL 0.8927 mL 1.7853 mL 4.4633 mL
50 mM 0.1428 mL 0.7141 mL 1.4283 mL 3.5707 mL
60 mM 0.1190 mL 0.5951 mL 1.1902 mL 2.9756 mL
80 mM 0.0893 mL 0.4463 mL 0.8927 mL 2.2317 mL
100 mM 0.0714 mL 0.3571 mL 0.7141 mL 1.7853 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Phosphonoacetic acid
Cat. No.:
HY-128744
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