Phosphonoacetic acid

Name: Phosphonoacetic acid
Brand: MedChemExpress
SKU: HY-128744
Rating: 4.5 (1 reviews)

Cat. No.: HY-128744 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Phosphonoacetic acid is an endogenous metabolite. Phosphonoacetic acid also has anti-orthopoxvirus activity.

For research use only. We do not sell to patients.

Phosphonoacetic acid Chemical Structure

CAS No. : 4408-78-0

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Phosphonoacetic acid is an endogenous metabolite. Phosphonoacetic acid also has anti-orthopoxvirus activity^[1].

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

140.03

Formula

C₂H₅O₅P

CAS No.

4408-78-0

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)CP(O)(O)=O

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Microorganisms

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 260 mg/mL (1856.74 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.1413 mL	35.7066 mL	71.4133 mL
5 mM	1.4283 mL	7.1413 mL	14.2827 mL
10 mM	0.7141 mL	3.5707 mL	7.1413 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (714.13 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (269 KB) SDS (416 KB)

COA (246 KB) HNMR (234 KB)

Handling Instructions (2659 KB)

References

[1]. Donald F Smee, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	7.1413 mL	35.7066 mL	71.4133 mL	178.5332 mL
	5 mM	1.4283 mL	7.1413 mL	14.2827 mL	35.7066 mL
	10 mM	0.7141 mL	3.5707 mL	7.1413 mL	17.8533 mL
	15 mM	0.4761 mL	2.3804 mL	4.7609 mL	11.9022 mL
	20 mM	0.3571 mL	1.7853 mL	3.5707 mL	8.9267 mL
	25 mM	0.2857 mL	1.4283 mL	2.8565 mL	7.1413 mL
	30 mM	0.2380 mL	1.1902 mL	2.3804 mL	5.9511 mL
	40 mM	0.1785 mL	0.8927 mL	1.7853 mL	4.4633 mL
	50 mM	0.1428 mL	0.7141 mL	1.4283 mL	3.5707 mL
	60 mM	0.1190 mL	0.5951 mL	1.1902 mL	2.9756 mL
	80 mM	0.0893 mL	0.4463 mL	0.8927 mL	2.2317 mL
	100 mM	0.0714 mL	0.3571 mL	0.7141 mL	1.7853 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.