2. PI3K/Akt/mTOR
  3. PI3K
  4. PI3K-IN-32

PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC50 of 6.85.

For research use only. We do not sell to patients.

PI3K-IN-32 Chemical Structure

PI3K-IN-32 Chemical Structure

CAS No. : 371934-59-7

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5 mg USD 680 In-stock
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Based on 1 publication(s) in Google Scholar

PI3K-IN-32 Related Antibodies

Top Publications Citing Use of Products

View All PI3K Isoform Specific Products:

View All Isoforms
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Description

PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC50 of 6.85[1].

Molecular Weight

347.37

Formula

C19H17N5O2
CAS No.
Appearance

Solid

Color

Light yellow to light brown

SMILES

NC1=CC=CC(C2=NC(N3CCOCC3)=C(OC4=NC=CC=C45)C5=N2)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 3.5 mg/mL (10.08 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8788 mL 14.3939 mL 28.7877 mL
5 mM 0.5758 mL 2.8788 mL 5.7575 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.7%

SDS (393 KB)

COA (255 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8788 mL 14.3939 mL 28.7877 mL 71.9694 mL
5 mM 0.5758 mL 2.8788 mL 5.7575 mL 14.3939 mL
10 mM 0.2879 mL 1.4394 mL 2.8788 mL 7.1969 mL
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PI3K-IN-32 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PI3K-IN-32371934-59-7PI3KPhosphoinositide 3-kinasephosphoinositide 3-kinase p110α3D-QSAR modelInhibitorinhibitorinhibit

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HY-103030
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