2. Immunology/Inflammation
  3. COX
  4. Piroxicam-d3

Piroxicam-d3  (Synonyms: CP-16171 d3)

Cat. No.: HY-B0253S Purity: 99.68%
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Piroxicam-d3 is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively [1].

For research use only. We do not sell to patients.

Piroxicam-d<sub>3</sub> Chemical Structure

Piroxicam-d3 Chemical Structure

CAS No. : 942047-64-5

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1 mg USD 150 In-stock
5 mg USD 560 In-stock
10 mg USD 950 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Piroxicam-d3:

Piroxicam-d3 Related Antibodies

Top Publications Citing Use of Products

View All COX Isoform Specific Products:

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COX COX-1 COX-2 COX-3

  • Biological Activity

  • Purity & Documentation

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Description

Piroxicam-d3 is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively [1].

Molecular Weight

334.36

Formula

C15H10D3N3O4S
CAS No.
Unlabeled CAS

36322-90-4
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C(O)C2=CC=CC=C2S(N1C([2H])([2H])[2H])(=O)=O)NC3=NC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (149.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (149.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.1 mg/mL (0.30 mM; Need ultrasonic)

H2O : 0.1 mg/mL (0.30 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9908 mL 14.9539 mL 29.9079 mL
5 mM 0.5982 mL 2.9908 mL 5.9816 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 2.9908 mL 14.9539 mL 29.9079 mL 74.7697 mL
5 mM 0.5982 mL 2.9908 mL 5.9816 mL 14.9539 mL
10 mM 0.2991 mL 1.4954 mL 2.9908 mL 7.4770 mL
15 mM 0.1994 mL 0.9969 mL 1.9939 mL 4.9846 mL
20 mM 0.1495 mL 0.7477 mL 1.4954 mL 3.7385 mL
25 mM 0.1196 mL 0.5982 mL 1.1963 mL 2.9908 mL
30 mM 0.0997 mL 0.4985 mL 0.9969 mL 2.4923 mL
40 mM 0.0748 mL 0.3738 mL 0.7477 mL 1.8692 mL
50 mM 0.0598 mL 0.2991 mL 0.5982 mL 1.4954 mL
60 mM 0.0498 mL 0.2492 mL 0.4985 mL 1.2462 mL
80 mM 0.0374 mL 0.1869 mL 0.3738 mL 0.9346 mL
100 mM 0.0299 mL 0.1495 mL 0.2991 mL 0.7477 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Piroxicam-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Piroxicam-d3942047-64-5CP-16171 d3COXCyclooxygenaseInhibitorinhibitorinhibit

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