2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. PNU-100440

PNU-100440 is the metabolite of Linezolid (HY-10394).

For research use only. We do not sell to patients.

PNU-100440 Chemical Structure

PNU-100440 Chemical Structure

CAS No. : 168828-82-8

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

PNU-100440 Related Antibodies

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Description

PNU-100440 is the metabolite of Linezolid (HY-10394)[1].

Molecular Weight

296.29

Formula

C14H17FN2O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C1O[C@H](CN1C2=CC=C(C(F)=C2)N3CCOCC3)CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (337.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3751 mL 16.8754 mL 33.7507 mL
5 mM 0.6750 mL 3.3751 mL 6.7501 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3751 mL 16.8754 mL 33.7507 mL 84.3768 mL
5 mM 0.6750 mL 3.3751 mL 6.7501 mL 16.8754 mL
10 mM 0.3375 mL 1.6875 mL 3.3751 mL 8.4377 mL
15 mM 0.2250 mL 1.1250 mL 2.2500 mL 5.6251 mL
20 mM 0.1688 mL 0.8438 mL 1.6875 mL 4.2188 mL
25 mM 0.1350 mL 0.6750 mL 1.3500 mL 3.3751 mL
30 mM 0.1125 mL 0.5625 mL 1.1250 mL 2.8126 mL
40 mM 0.0844 mL 0.4219 mL 0.8438 mL 2.1094 mL
50 mM 0.0675 mL 0.3375 mL 0.6750 mL 1.6875 mL
60 mM 0.0563 mL 0.2813 mL 0.5625 mL 1.4063 mL
80 mM 0.0422 mL 0.2109 mL 0.4219 mL 1.0547 mL
100 mM 0.0338 mL 0.1688 mL 0.3375 mL 0.8438 mL
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PNU-100440 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PNU-100440168828-82-8PNU100440PNU 100440Endogenous MetaboliteLinezolidInhibitorinhibitorinhibit

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