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  3. Biochemical Assay Reagents
  4. Poly-L-lysine hydrobromide (MW 150000-300000)

Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface.

For research use only. We do not sell to patients.

Poly-L-lysine hydrobromide (MW 150000-300000) Chemical Structure

Poly-L-lysine hydrobromide (MW 150000-300000) Chemical Structure

CAS No. : 25988-63-0

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Other Forms of Poly-L-lysine hydrobromide (MW 150000-300000):

Poly-L-lysine hydrobromide (MW 150000-300000) Related Antibodies

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Description

Poly-L-lysine (hydrobromide) (MW 150000-300000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 150000-300000) has good biocompatibility. Poly-L-lysine (hydrobromide) (MW 150000-300000) is used to increase cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface[1].

In Vitro

Poly-L-lysine (hydrobromide) (MW 150000-300000) binds to the hydroxyl groups on the surface of magnetic nanoparticles through its amino groups, forms a stable coating layer, prevents the agglomeration and sedimentation of magnetic nanoparticles. Poly-L-lysine (hydrobromide) (MW 150000-300000) modifies magnetic nanoparticles, improves biocompatibility, and can be used as an antibody coupling platform[2].
Poly-L-lysine (hydrobromide) (MW 150000-300000) acts as a cationic polymer, forms a polyelectrolyte complex (PEC) with anionic methacrylated gellan gum (GG-MA), thereby forming a semipermeable membrane around the GG-MA hydrogel. Poly-L-lysine (hydrobromide) (MW 150000-300000) regulate the permeability of GG-MA/PLL PEC beads, allowing the free diffusion of small molecules while preventing the entry of large molecules, thereby achieving the immune isolation of cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Poly-L-lysine hydrobromide (MW 150000-300000) Related Antibodies
Molecular Weight

150000-300000

Formula

C8H19BrN2O
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

CN[C@@H](CCCC[NH3+])C(C)=O.[n].[Br-].[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (Need ultrasonic)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL; Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL; Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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Poly-L-lysine hydrobromide (MW 150000-300000) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Poly-L-lysine hydrobromide (MW 150000-300000)25988-63-0Biochemical Assay Reagentsattachment factor for cellscell adhesionInhibitorinhibitorinhibit

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Poly-L-lysine hydrobromide (MW 150000-300000)
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