2. PROTAC
  3. Ligands for E3 Ligase
  4. Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride

Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride 

Cat. No.: HY-163210
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Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride (ZJT1) is an E3 ubiquitin ligase cereblon based on Pomalidomide (HY-10984) (CRBN) ligand for recruitment of cereblon protein. Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride can be linked to protein ligand by linker to form PROTAC.

For research use only. We do not sell to patients.

Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride Chemical Structure

Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride Chemical Structure

CAS No. : 2758431-94-4

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Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon IAP

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Description

Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride (ZJT1) is an E3 ubiquitin ligase cereblon based on Pomalidomide (HY-10984) (CRBN) ligand for recruitment of cereblon protein. Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride can be linked to protein ligand by linker to form PROTAC[1].

Molecular Weight

530.42

Formula

C23H30Cl2FN5O4
CAS No.
SMILES

O=C1NC(C(CC1)N2C(C3=CC(F)=C(N4CCN(CC5CCNCC5)CC4)C=C3C2=O)=O)=O.Cl.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine hydrochloride Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine2758431-94-4Ligands for E3 LigaseE3 ligase-recruiting MoietyCRBNcereblon PROTACPomalidomide linkerligandInhibitorinhibitorinhibit

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