1. Neuronal Signaling
  2. Cholinesterase (ChE)
  3. Pralidoxime methanesulfonate

Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime methanesulfonate reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime methanesulfonate is an antidote for organophosphate poisoning.

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Pralidoxime methanesulfonate Chemical Structure

Pralidoxime methanesulfonate Chemical Structure

CAS No. : 154-97-2

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Description

Pralidoxime methanesulfonate is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime methanesulfonate reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime methanesulfonate is an antidote for organophosphate poisoning[1][2].

Molecular Weight

232.26

Formula

C8H12N2O4S

CAS No.
SMILES

O=S([O-])(C)=O.O/N=C/C1=[N+](C)C=CC=C1

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Pralidoxime methanesulfonate Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Pralidoxime methanesulfonate
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HY-B1738B
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