2. Epigenetics
  3. Histone Methyltransferase
  4. PRMT1-IN-2

PRMT1-IN-2 (RM65) is a potent PRMT1 inhibitor with an IC50 of 55.4 μM. PRMT1-IN-2 shows histone hypomethylation in HepG2 cells.

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PRMT1-IN-2 Chemical Structure

PRMT1-IN-2 Chemical Structure

CAS No. : 947508-41-0

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PRMT1-IN-2 Related Antibodies

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View All Histone Methyltransferase Isoform Specific Products:

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EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

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Description

PRMT1-IN-2 (RM65) is a potent PRMT1 inhibitor with an IC50 of 55.4 μM. PRMT1-IN-2 shows histone hypomethylation in HepG2 cells[1].

Molecular Weight

596.76

Formula

C34H32N2O4S2
CAS No.
SMILES

O=C(C(C)SC1C2=C(OC3=C1C=CC=C3)C=CC=C2)NCCNC(C(C)SC4C5=C(OC6=C4C=CC=C6)C=CC=C5)=O
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Purity & Documentation
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PRMT1-IN-2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PRMT1-IN-2947508-41-0Histone MethyltransferaseHepG2arginine methyltransferasePRMTRM65Inhibitorinhibitorinhibit

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