2. Epigenetics
  3. Histone Methyltransferase
  4. PRMT5-IN-43

PRMT5-IN-43 (compound 4A) is a PRMT5 inhibitor. PRMT5-IN-43 can be used in cancer research.

For research use only. We do not sell to patients.

PRMT5-IN-43 Chemical Structure

PRMT5-IN-43 Chemical Structure

CAS No. : 3034746-11-4

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PRMT5-IN-43 Related Antibodies

Top Publications Citing Use of Products

View All Histone Methyltransferase Isoform Specific Products:

View All Isoforms
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

  • Biological Activity

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Description

PRMT5-IN-43 (compound 4A) is a PRMT5 inhibitor. PRMT5-IN-43 can be used in cancer research[1].

IC50 & Target

PRMT5

 

Molecular Weight

475.85

Formula

C22H17ClF3N5O2
CAS No.
SMILES

O=C(N1[C@@H](C2=CC=C(C=C2)C(F)(F)F)COCC1)C3=C(Cl)C=C4N=C(N)C5=CN=CN5C4=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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PRMT5-IN-43 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PRMT5-IN-433034746-11-4Histone MethyltransferaseDNA methylationhistone acetylation and methylationnoncoding RNApost-translational modificationsInhibitorinhibitorinhibit

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