1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Propionylpromazine-d6 hydrochloride

Propionylpromazine-d6 hydrochloride 

Cat. No.: HY-W040146S Purity: 99.78%
COA Handling Instructions

Propionylpromazine-d6 (hydrochloride) is the deuterium labeled Propionylpromazine hydrochloride. Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].

For research use only. We do not sell to patients.

Propionylpromazine-d<sub>6</sub> hydrochloride Chemical Structure

Propionylpromazine-d6 hydrochloride Chemical Structure

CAS No. : 1262770-67-1

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1 mg USD 380 In-stock
5 mg USD 850 In-stock
10 mg USD 1480 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Propionylpromazine-d6 hydrochloride:

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Propionylpromazine-d6 hydrochloride

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Propionylpromazine-d6 (hydrochloride) is the deuterium labeled Propionylpromazine hydrochloride. Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease[1].

IC50 & Target

D2 Receptor

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

382.98

Formula

C20H19D6ClN2OS

CAS No.
Unlabeled CAS

7681-67-6

Appearance

Solid

Color

Light yellow to yellow

SMILES

[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCCN1C2=CC(C(CC)=O)=CC=C2SC3=CC=CC=C31.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 8.33 mg/mL (21.75 mM; Need ultrasonic)

H2O : 8.33 mg/mL (21.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6111 mL 13.0555 mL 26.1110 mL
5 mM 0.5222 mL 2.6111 mL 5.2222 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 2.6111 mL 13.0555 mL 26.1110 mL 65.2776 mL
5 mM 0.5222 mL 2.6111 mL 5.2222 mL 13.0555 mL
10 mM 0.2611 mL 1.3056 mL 2.6111 mL 6.5278 mL
15 mM 0.1741 mL 0.8704 mL 1.7407 mL 4.3518 mL
20 mM 0.1306 mL 0.6528 mL 1.3056 mL 3.2639 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Propionylpromazine-d6 hydrochloride
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HY-W040146S
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