1. PROTAC
  2. PROTAC Linkers
  3. Tetraethylene glycol

Tetraethylene glycol  (Synonyms: PROTAC Linker 18)

Cat. No.: HY-W018745 Purity: 99.97%
COA Handling Instructions

Tetraethylene glycol (PROTAC Linker 18) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Tetraethylene glycol Chemical Structure

Tetraethylene glycol Chemical Structure

CAS No. : 112-60-7

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Description

Tetraethylene glycol (PROTAC Linker 18) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

194.23

Formula

C8H18O5

CAS No.
Appearance

Liquid (Density: 1.125 g/cm3)

Color

Colorless to light yellow

SMILES

OCCOCCOCCOCCO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.97%

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tetraethylene glycol
Cat. No.:
HY-W018745
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