2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Angiopoietins
  5. Angiopoietin-Like 7

Angiopoietin-Like 7

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Angiopoietin-like proteins (ANGPTLs) are identified as a family of proteins structurally similar to the angiopoietins. Eight ANGPTLs have been discovered, namely ANGPTL1 to ANGPTL8. ANGPTLs do not bind to the receptors classically targeted by angiopoietins, Tie-1/2, and have been generally considered orphan ligands. Similar to angiopoietins, ANGPTLs are able to potently regulate angiogenesis.
Most of the ANGPTLs exhibit multibiological properties, including established functional roles in lipid and glucose metabolism, inflammation, hematopoiesis, and cancer. For example, ANGPTL 2, 3, 4, 6 and 7 are pro-inflammatory factors and regulate cancer progression, while ANGPTL1 inhibits tumor angiogenesis and metastasis.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P7509
    ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His)

    rHuAngiopoietin-related Protein 7, His; ANGPTL7; Angiopoietin-related Protein 7

    		Human HEK293
    ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His) regulates angiogenesis, and promotes the expansion and repopulation of human hematopoietic stem cells and progenitor cells through the Wnt signaling pathway. Angiopoietin-related Protein 7 is a pro-inflammatory effector that induces inflammatory responses in macrophages through the P38 MAPK signaling pathway.
  • HY-P75506
    ANGPTL7/Angiopoietin-related 7 Protein, Rhesus Macaque (HEK293, His)

    Angiopoietin like 7; ANGPTL7; CDT6

    		Rhesus Macaque HEK293
    ANGPTL7/angiopoietin-related 7 protein plays a crucial role in the formation and organization of the extracellular matrix. Particularly in the eye, it serves as a mediator for dexamethasone-induced matrix deposition within the trabecular meshwork, a tissue that studies have shown is necessary for aqueous humor outflow and maintenance of intraocular pressure. ANGPTL7/Angiopoietin-related 7 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P75507
    ANGPTL7/Angiopoietin-related 7 Protein, Canine (HEK293, His)

    Angiopoietin-like factor; ANGPTL7; AngX; CDT6

    		Canine HEK293
    ANGPTL7/ Angiopoietin-related proteins are negative regulators of corneal angiogenesis and play an important role in maintaining the patency and transparency of corneal blood vessels. ANGPTL7 is regulated by SP1 transcription and regulates ANGPTL7 levels through the RhoA/ROCK signaling pathway mediating CLAN formation. ANGPTL7/Angiopoietin-related 7 Protein, Canine (HEK293, His) is the recombinant canine-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P700852
    ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, hFc)

    angiopoietin-like 7; Angiopoietin-like factor; ANGPTL7; AngX; CDT6

    		Human HEK293
    ANGPTL7/angiopoietin-related 7 protein plays a crucial role in the formation and organization of the extracellular matrix. Particularly in the eye, it serves as a mediator for dexamethasone-induced matrix deposition within the trabecular meshwork, a tissue that studies have shown is necessary for aqueous humor outflow and maintenance of intraocular pressure. ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, hFc) is the recombinant human-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, hFc) is 320 a.a., with molecular weight of 70-90 kDa.
  • HY-P700955
    ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His-Avi)

    angiopoietin-like 7; Angiopoietin-like factor; ANGPTL7; AngX; CDT6

    		Human HEK293
    ANGPTL7/angiopoietin-related 7 protein plays a crucial role in the formation and organization of the extracellular matrix. Particularly in the eye, it serves as a mediator for dexamethasone-induced matrix deposition within the trabecular meshwork, a tissue that studies have shown is necessary for aqueous humor outflow and maintenance of intraocular pressure. ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His-Avi) is the recombinant human-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of ANGPTL7/Angiopoietin-related 7 Protein, Human (HEK293, His-Avi) is 320 a.a., with molecular weight of 35-40 kDa.
  • HY-P75508
    ANGPTL7/Angiopoietin-related 7 Protein, Canine (HEK293, Fc)

    Angiopoietin-like factor; ANGPTL7; AngX; CDT6

    		Canine HEK293
    ANGPTL7/ Angiopoietin-related proteins are negative regulators of corneal angiogenesis and play an important role in maintaining the patency and transparency of corneal blood vessels. ANGPTL7 is regulated by SP1 transcription and regulates ANGPTL7 levels through the RhoA/ROCK signaling pathway mediating CLAN formation. ANGPTL7/Angiopoietin-related 7 Protein, Canine (HEK293, Fc) is the recombinant canine-derived ANGPTL7/Angiopoietin-related 7 protein, expressed by HEK293 , with C-hFc labeled tag.
Cat. No. Product Name Effect Purity