2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-17
  6. IL-17B

IL-17B

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Interleukin-17B (IL-17B) belongs to the IL-17 cytokine family and is a proinflammatory cytokine. IL-17B is expressed in adult pancreas, small intestine, stomach, spinal cord and testis. And IL-17B is less pronounced expression in prostate, colon mucosal lining, and ovary. IL-17B was never detected in activated CD4 T cells[1][2]. IL-17B is secreted as a non-covalent dimer glycoprotein[2]. IL-17B shares about 27% amino acid identity with IL-17A and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β in the THP-1 monocytic cell line[1]. The receptor of IL-17B is IL-17RB, which belongs to the IL-17 receptor family. IL-17B shares IL-17RB with IL-17E. IL-17B inhibits IL-17E binding to IL-17RA/IL-17RB complexes, exhibits protumor roles and IL-17E antitumor activities[2]. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis[1]. Human and mouse IL-17B shares 88.33% sequence identity.

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Cat. No. Product Name / Synonyms Species Source
  • HY-P72588
    IL-17B Protein, Human (HEK293, Fc)

    Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7

    		Human HEK293
    IL-17B is a proinflammatory cytokine and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis. IL-17B Protein, Human (HEK293, Fc) is a recombinant human IL-17B protein with hFc tag at the C-terminus and is expressed in HEK293 cells.
  • HY-P75835
    IL-17B Protein, Mouse (sf9, Fc)

    Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7

    		Mouse Sf9 insect cells
    IL-17B is a proinflammatory cytokine and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis. IL-17B Protein, Mouse (sf9, Fc) is a recombinant mouse IL-17B protein with hFc tag at the C-terminus and is expressed in Sf9 insect cells. It consists of 180 amino acids (M1-F180).
  • HY-P700105AF
    Animal-Free IL-17B Protein, Human (His)

    Interleukin-17B; IL-17B; Cytokine Zcyto7; IL-20; NIRF; ZCYTO7

    		Human E. coli
    IL-17B Proteinas, crucial in cellular signaling, induces the release of pro-inflammatory cytokines, TNF-α, and IL-1β from THP-1 monocytic cells.Its role in regulating immune responses and inflammatory processes underscores its potential significance in mediating crosstalk between immune cells, contributing to overall immune homeostasis.Animal-Free IL-17B Protein, Human (His) is the recombinant human-derived animal-FreeIL-17B protein, expressed by E.coli , with C-His labeled tag.
  • HY-P78315
    IL-17B Protein, Mouse (His)

    IL-17B; Cytokine CX1; IL20; interleukin 17B; interleukin 20; MGC138900; MGC138901; NIRF; ZCYTO7

    		Mouse E. coli
    IL-17B is a proinflammatory cytokine and stimulates the release of tumour necrosis factor alpha (TNFα) and IL-1β. IL-17B plays an important role in cancer progression, angiogenesis, and inflammatory arthritis. IL-17B Protein, Mouse (His) is a recombinant mouse IL-17B protein with His tag at the N-terminus and is expressed in E. coli. It consists of 160 amino acids (H21-F180).
  • HY-P78315AF
    Animal-Free IL-17B Protein, Mouse (His)

    IL-17B; Cytokine CX1; IL20; interleukin 17B; interleukin 20; MGC138900; MGC138901; NIRF; ZCYTO7

    		Mouse E. coli
    IL-17B Proteinas, a key immune response regulator, stimulates THP-1 monocytic cells to release pro-inflammatory cytokines, TNF-α, and IL-1β. Its crucial role in orchestrating immune reactions and inflammatory pathways positions it as a potential modulator of immune homeostasis, making it a therapeutic intervention target for regulating inflammatory processes. Animal-Free IL-17B Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-17B protein, expressed by E. coli , with C-His, C-His labeled tag. The total length of Animal-Free IL-17B Protein, Mouse (His) is 160 a.a., with molecular weight of ~18.99 kDa.
Cat. No. Product Name Effect Purity