2. Recombinant Proteins
  3. Immune Checkpoint Proteins CD Antigens
  4. Inhibitory Checkpoint Molecules NK Cell CD Proteins Macrophage CD Proteins
  5. LAG-3/CD223

LAG-3/CD223

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Lymphocyte activation gene-3 (LAG-3, also known as CD223), an inhibitory checkpoint, is a type I transmembrane protein expressed on activated T cells, B cells, natural killer (NK) cells, and plasmacytoid dendritic cells (pDCs). LAG-3 is a member of the im

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Cat. No. Product Name / Synonyms Species Source
  • HY-P70723
    LAG-3 Protein, Human (HEK293, Fc)

    Lymphocyte activation gene 3 protein; LAG3; LAG-3; Protein FDC; CD223

    		Human HEK293
    LAG-3 (lymphocyte activating gene 3) protein is an inhibitory receptor on antigen-activated T cells and is critical for immune regulation. LAG-3 binds to FGL1 and transmits inhibitory signals that negatively affect CD8(+) and CD4(+) T cell proliferation, activation, and effector functions. LAG-3 Protein, Human (HEK293, Fc) is the recombinant human-derived LAG-3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of LAG-3 Protein, Human (HEK293, Fc) is 428 a.a., with molecular weight of 70-90 kDa.
  • HY-P78656
    LAG-3 Protein, Marmoset (HEK293, His)

    LAG3; CD223; FDC

    		Marmoset HEK293
    LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1. FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells. LAG-3 Protein, Marmoset (HEK293, His) is the recombinant Marmoset-derived LAG-3 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of LAG-3 Protein, Marmoset (HEK293, His) is 432 a.a., with molecular weight of ~57 kDa.
  • HY-P70722
    LAG-3 Protein, Human (HEK293, His)

    Lymphocyte activation gene 3 protein; LAG3; LAG-3; Protein FDC; CD223

    		Human HEK293
    LAG-3 (lymphocyte activating gene 3) protein is an inhibitory receptor on antigen-activated T cells and is critical for immune regulation. LAG-3 binds to FGL1 and transmits inhibitory signals that negatively affect CD8(+) and CD4(+) T cell proliferation, activation, and effector functions. LAG-3 Protein, Human (HEK293, His) is the recombinant human-derived LAG-3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LAG-3 Protein, Human (HEK293, His) is 428 a.a., with molecular weight of 60-80 kDa.
  • HY-P73843
    LAG-3 Protein, Mouse (HEK293, Fc)

    Lymphocyte activation gene 3 protein; Protein FDC; CD223

    		Mouse HEK293
    LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1.FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells.LAG-3 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived LAG-3 protein, expressed by HEK293 , with C-hFc labeled tag.
  • HY-P78720
    LAG-3 Protein, Mouse (419a.a, HEK293, His)

    Lymphocyte activation gene 3 protein; LAG3; LAG-3; Protein FDC; CD223

    		Mouse HEK293
    LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1.FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells.LAG-3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived LAG-3 protein, expressed by HEK293 , with C-His labeled tag.
  • HY-P72530
    LAG-3 Protein, Cynomolgus (428a.a, HEK293, His)

    Lymphocyte Activating 3; LAG3; LAG-3; CD223

    		Cynomolgus HEK293
    LAG-3 Protein, expressed on antigen-activated T-cells, delivers inhibitory signals by binding to ligands like FGL1. LAG-3 Protein associates with CD3-TCR, directly inhibiting T-cell activation. LAG-3 Protein, Cynomolgus (428a.a, HEK293, His) is a recombinant protein dimer complex containing cynomolgus-derived LAG-3 protein, expressed by HEK293 , with N-8*His labeled tag. LAG-3 Protein, Cynomolgus (428a.a, HEK293, His), has molecular weight of 55-65 kDa.
  • HY-P70735
    LAG-3 Protein, Human (HEK293, mFc)

    Lymphocyte activation gene 3 protein; LAG3; LAG-3; Protein FDC; CD223

    		Human HEK293
    LAG-3 (lymphocyte activating gene 3) protein is an inhibitory receptor on antigen-activated T cells and is critical for immune regulation. LAG-3 binds to FGL1 and transmits inhibitory signals that negatively affect CD8(+) and CD4(+) T cell proliferation, activation, and effector functions. LAG-3 Protein, Human (HEK293, mFc) is the recombinant human-derived LAG-3 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of LAG-3 Protein, Human (HEK293, mFc) is 428 a.a., with molecular weight of ~90.0 kDa.
  • HY-P72389
    LAG-3 Protein, Human (Biotinylated, HEK293, His-Avi)

    Lymphocyte activation gene 3 protein; Protein FDC; CD223

    		Human HEK293
    LAG-3 (lymphocyte activating gene 3) protein is an inhibitory receptor on antigen-activated T cells and is critical for immune regulation. LAG-3 binds to FGL1 and transmits inhibitory signals that negatively affect CD8(+) and CD4(+) T cell proliferation, activation, and effector functions. LAG-3 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived LAG-3 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of LAG-3 Protein, Human (Biotinylated, HEK293, His-Avi) is 428 a.a., with molecular weight of 60-70 kDa.
  • HY-P73844
    LAG-3 Protein, Mouse (HEK293)

    Lymphocyte activation gene 3 protein; Protein FDC; CD223

    		Mouse HEK293
    LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1.FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells.LAG-3 Protein, Mouse (HEK293) is the recombinant mouse-derived LAG-3 protein, expressed by HEK293 , with tag free.
  • HY-P74788
    LAG-3 Protein, Rat (HEK293, His)

    Lymphocyte activation gene 3 protein; Protein FDC; CD223

    		Rat HEK293
    LAG-3 (lymphocyte activation gene 3) protein is an inhibitory receptor on antigen-activated T cells, which transmits inhibitory signals by binding to ligands such as FGL1. LAG-3 is associated with CD3-TCR at the immune synapse, hinders T cell activation, and may cooperate with PDCD1/PD-1 to act as a co-receptor for PD-1. LAG-3 Protein, Rat (HEK293, His) is the recombinant rat-derived LAG-3 protein, expressed by HEK293 , with C-His labeled tag.
Cat. No. Product Name Effect Purity