2. Neuronal Signaling
  3. CaMK
  4. PTCA

PTCA is a potent Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα) ligand with a pKi value of 7.2.

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PTCA Chemical Structure

PTCA Chemical Structure

CAS No. : 871326-47-5

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Description

PTCA is a potent Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα) ligand with a pKi value of 7.2[1].

Molecular Weight

274.12

Formula

C10H5Cl2NO2S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CSC(C2=C(Cl)C=CC=C2Cl)=N1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (364.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6480 mL 18.2402 mL 36.4804 mL
5 mM 0.7296 mL 3.6480 mL 7.2961 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6480 mL 18.2402 mL 36.4804 mL 91.2009 mL
5 mM 0.7296 mL 3.6480 mL 7.2961 mL 18.2402 mL
10 mM 0.3648 mL 1.8240 mL 3.6480 mL 9.1201 mL
15 mM 0.2432 mL 1.2160 mL 2.4320 mL 6.0801 mL
20 mM 0.1824 mL 0.9120 mL 1.8240 mL 4.5600 mL
25 mM 0.1459 mL 0.7296 mL 1.4592 mL 3.6480 mL
30 mM 0.1216 mL 0.6080 mL 1.2160 mL 3.0400 mL
40 mM 0.0912 mL 0.4560 mL 0.9120 mL 2.2800 mL
50 mM 0.0730 mL 0.3648 mL 0.7296 mL 1.8240 mL
60 mM 0.0608 mL 0.3040 mL 0.6080 mL 1.5200 mL
80 mM 0.0456 mL 0.2280 mL 0.4560 mL 1.1400 mL
100 mM 0.0365 mL 0.1824 mL 0.3648 mL 0.9120 mL
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PTCA Related Classifications

Keywords:

PTCA871326-47-5CaMKCalmodulin-dependent protein kinasesCalmodulin-dependent kinasesCaMKIIα LigandInhibitorinhibitorinhibit

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