2. Others
  3. Fluorescent Dye
  4. pyCTZ

pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing.

For research use only. We do not sell to patients.

pyCTZ Chemical Structure

pyCTZ Chemical Structure

CAS No. : 2125486-34-0

Size Price Stock Quantity
1 mg USD 130 In-stock
5 mg USD 300 In-stock
10 mg USD 520 In-stock
25 mg USD 980 In-stock
50 mg USD 1450 In-stock
100 mg USD 2130 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of pyCTZ:

pyCTZ Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing[1].

In Vitro

pyCTZ is comparable to native CTZ for bioluminescence intensity when pairs with aequorin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

pyCTZ Related Antibodies
Molecular Weight

392.45

Formula

C25H20N4O
CAS No.
Appearance

Solid

Color

Light green to green

SMILES

O=C1C(CC2=CC=NC=C2)=NC3=C(CC4=CC=CC=C4)NC(C5=CC=CC=C5)=CN31
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

Methanol : 41.67 mg/mL (106.18 mM; Need ultrasonic)

DMSO : 33.33 mg/mL (84.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5481 mL 12.7405 mL 25.4810 mL
5 mM 0.5096 mL 2.5481 mL 5.0962 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / Methanol 1 mM 2.5481 mL 12.7405 mL 25.4810 mL 63.7024 mL
5 mM 0.5096 mL 2.5481 mL 5.0962 mL 12.7405 mL
10 mM 0.2548 mL 1.2740 mL 2.5481 mL 6.3702 mL
15 mM 0.1699 mL 0.8494 mL 1.6987 mL 4.2468 mL
20 mM 0.1274 mL 0.6370 mL 1.2740 mL 3.1851 mL
25 mM 0.1019 mL 0.5096 mL 1.0192 mL 2.5481 mL
30 mM 0.0849 mL 0.4247 mL 0.8494 mL 2.1234 mL
40 mM 0.0637 mL 0.3185 mL 0.6370 mL 1.5926 mL
50 mM 0.0510 mL 0.2548 mL 0.5096 mL 1.2740 mL
60 mM 0.0425 mL 0.2123 mL 0.4247 mL 1.0617 mL
80 mM 0.0319 mL 0.1593 mL 0.3185 mL 0.7963 mL
Methanol 100 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.6370 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

pyCTZ Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

pyCTZ2125486-34-0Pyridyl CTZFluorescent DyepyridylCoelenterazineCTZsubstrateLumiLucluciferasebluebioluminescenceaequorin-basedcalciumInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
pyCTZ
Cat. No.:
HY-135367
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.