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  5. Pyrogallol-phloroglucinol-6,6-bieckol

Pyrogallol-phloroglucinol-6,6-bieckol 

Cat. No.: HY-N11729 Purity: ≥80.0%
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Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia.

For research use only. We do not sell to patients.

Pyrogallol-phloroglucinol-6,6-bieckol Chemical Structure

Pyrogallol-phloroglucinol-6,6-bieckol Chemical Structure

CAS No. : 1415504-32-3

Size Price Stock Quantity
1 mg USD 270 In-stock
5 mg USD 670 In-stock
10 mg USD 1080 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Pyrogallol-phloroglucinol-6,6-bieckol Related Antibodies

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Description

Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia[1].

Molecular Weight

974.74

Formula

C48H30O23
CAS No.
Appearance

Solid

Color

Light yellow to brown

SMILES

OC1=CC(OC2=C(C=C(C=C2O)OC3=CC(O)=CC(OC4=C(C=C(C(OC5=C(C6=C(C=C(C7=C6OC8=C(C(OC9=CC(O)=CC(O)=C9)=C(C=C8O)O)O7)O)O)C(O)=C%10)=C4OC5=C%10O)O)O)=C3)O)=CC(O)=C1
Structure Classification
Initial Source

Ecklonia cava
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (102.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0259 mL 5.1296 mL 10.2591 mL
5 mM 0.2052 mL 1.0259 mL 2.0518 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (2.56 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.0259 mL 5.1296 mL 10.2591 mL 25.6479 mL
5 mM 0.2052 mL 1.0259 mL 2.0518 mL 5.1296 mL
10 mM 0.1026 mL 0.5130 mL 1.0259 mL 2.5648 mL
15 mM 0.0684 mL 0.3420 mL 0.6839 mL 1.7099 mL
20 mM 0.0513 mL 0.2565 mL 0.5130 mL 1.2824 mL
25 mM 0.0410 mL 0.2052 mL 0.4104 mL 1.0259 mL
30 mM 0.0342 mL 0.1710 mL 0.3420 mL 0.8549 mL
40 mM 0.0256 mL 0.1282 mL 0.2565 mL 0.6412 mL
50 mM 0.0205 mL 0.1026 mL 0.2052 mL 0.5130 mL
60 mM 0.0171 mL 0.0855 mL 0.1710 mL 0.4275 mL
80 mM 0.0128 mL 0.0641 mL 0.1282 mL 0.3206 mL
100 mM 0.0103 mL 0.0513 mL 0.1026 mL 0.2565 mL
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Pyrogallol-phloroglucinol-6,6-bieckol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrogallol-phloroglucinol-6,6-bieckol1415504-32-3OthersPhlorotanninsEckloniaAntioxidant AgentInhibitorinhibitorinhibit

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