2. Cell Cycle/DNA Damage Stem Cell/Wnt
  3. Casein Kinase
  4. Quinalizarin

Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells.

For research use only. We do not sell to patients.

Quinalizarin Chemical Structure

Quinalizarin Chemical Structure

CAS No. : 81-61-8

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Based on 1 publication(s) in Google Scholar

Quinalizarin Related Antibodies

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Description

Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1].

IC50 & Target[1]

CK2

~50 nM (Ki)

CK2

110 nM (IC50)

Molecular Weight

272.21

Formula

C14H8O6
CAS No.
Appearance

Solid

Color

Orange to reddish brown

SMILES

O=C1C2=C(C(O)=CC=C2O)C(C3=CC=C(O)C(O)=C13)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 10 mg/mL (36.74 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6736 mL 18.3682 mL 36.7363 mL
5 mM 0.7347 mL 3.6736 mL 7.3473 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 97.1%

COA (253 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6736 mL 18.3682 mL 36.7363 mL 91.8409 mL
5 mM 0.7347 mL 3.6736 mL 7.3473 mL 18.3682 mL
10 mM 0.3674 mL 1.8368 mL 3.6736 mL 9.1841 mL
15 mM 0.2449 mL 1.2245 mL 2.4491 mL 6.1227 mL
20 mM 0.1837 mL 0.9184 mL 1.8368 mL 4.5920 mL
25 mM 0.1469 mL 0.7347 mL 1.4695 mL 3.6736 mL
30 mM 0.1225 mL 0.6123 mL 1.2245 mL 3.0614 mL
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Quinalizarin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quinalizarin81-61-8Casein KinaseAnticancercell-permeableJurkatInhibitorinhibitorinhibit

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