1. Protein Tyrosine Kinase/RTK PROTAC Apoptosis Autophagy
  2. FLT3 Ligands for Target Protein for PROTAC Apoptosis Autophagy
  3. Quizartinib (Standard)

Quizartinib (Standard) is the analytical standard of Quizartinib. This product is intended for research and analytical applications. Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a Kd of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC50s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis.

For research use only. We do not sell to patients.

Quizartinib (Standard) Chemical Structure

Quizartinib (Standard) Chemical Structure

CAS No. : 950769-58-1

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5 mg USD 165 Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks
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50 mg USD 515 Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks
100 mg USD 720 Get quote 5 - 7 weeks 4 - 6 weeks 4 - 6 weeks
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Description
Molecular Weight

560.67

Formula

C29H32N6O4S

CAS No.
SMILES

O=C(NC1=NOC(C(C)(C)C)=C1)NC2=CC=C(C=C2)C3=CN4C(SC5=CC(OCCN6CCOCC6)=CC=C45)=N3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Quizartinib (Standard)
Cat. No.:
HY-13001R
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