2. Stem Cell/Wnt Apoptosis Neuronal Signaling
  3. Wnt c-Myc Notch
  4. RA-V

RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.

For research use only. We do not sell to patients.

RA-V Chemical Structure

RA-V Chemical Structure

CAS No. : 64725-24-2

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1 mg USD 420 In-stock
5 mg USD 1050 In-stock
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Based on 1 publication(s) in Google Scholar

RA-V Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

RA-V is a cyclic hexapeptide. RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways[1].

IC50 & Target

IC50: 50 ng/mL (Wnt); 75 ng/mL (Myc), 93 ng/mL (Notch)[1]
In Vivo

RA-V has activity against Wnt, Myc and Notch with IC50 values of 50, 75, and 93 ng/mL, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

756.84

Formula

C40H48N6O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=CC=C2C=C1OC3=CC=C(C[C@@]4(N(C([C@H](C)NC([C@@H](N(C([C@H](C)NC([C@@H](C)NC([C@]([H])(C2)N(C)C4=O)=O)=O)=O)C)CC5=CC=C(OC)C=C5)=O)=O)C)[H])C=C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (132.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3213 mL 6.6064 mL 13.2128 mL
5 mM 0.2643 mL 1.3213 mL 2.6426 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.63%

SDS (252 KB)

COA (257 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3213 mL 6.6064 mL 13.2128 mL 33.0321 mL
5 mM 0.2643 mL 1.3213 mL 2.6426 mL 6.6064 mL
10 mM 0.1321 mL 0.6606 mL 1.3213 mL 3.3032 mL
15 mM 0.0881 mL 0.4404 mL 0.8809 mL 2.2021 mL
20 mM 0.0661 mL 0.3303 mL 0.6606 mL 1.6516 mL
25 mM 0.0529 mL 0.2643 mL 0.5285 mL 1.3213 mL
30 mM 0.0440 mL 0.2202 mL 0.4404 mL 1.1011 mL
40 mM 0.0330 mL 0.1652 mL 0.3303 mL 0.8258 mL
50 mM 0.0264 mL 0.1321 mL 0.2643 mL 0.6606 mL
60 mM 0.0220 mL 0.1101 mL 0.2202 mL 0.5505 mL
80 mM 0.0165 mL 0.0826 mL 0.1652 mL 0.4129 mL
100 mM 0.0132 mL 0.0661 mL 0.1321 mL 0.3303 mL
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RA-V Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RA-V64725-24-2Wntc-MycNotchMyccyclic hexapeptidecancersignaling pathwaysInhibitorinhibitorinhibit

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