1. Anti-infection Metabolic Enzyme/Protease
  2. Fungal Cytochrome P450
  3. (Rac)-Ketoconazole

(Rac)-Ketoconazole  (Synonyms: (Rac)-Ketoconazol; (Rac)-R 41400)

Cat. No.: HY-W422288
Handling Instructions

(Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections.

For research use only. We do not sell to patients.

(Rac)-Ketoconazole Chemical Structure

(Rac)-Ketoconazole Chemical Structure

CAS No. : 79156-75-5

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Description

(Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections[1].

Molecular Weight

531.43

Formula

C26H28Cl2N4O4

CAS No.
SMILES

CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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(Rac)-Ketoconazole Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(Rac)-Ketoconazole
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