(±)-Acetylcarnitine chloride (Synonyms: Acetyl dl-carnitine chloride)

Cat. No.: HY-100907 Purity: 99.60%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with cholinergic properties. (±)-Acetylcarnitine chloride is an important intermediate in lipid metabolism.

For research use only. We do not sell to patients.

(±)-Acetylcarnitine chloride Chemical Structure

CAS No. : 2504-11-2

Size	Price	Stock	Quantity
5 mg	USD 33	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 48	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 84	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 118	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 166	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

Large increases of Acetylcarnitine concentration during the flight of the blowfly and the presence of an active Acetylcarnitine transferase indicate that Acetylcarnitine is important in carbohydrate metabolism. Acetylcarnitine has been synthesized by the choline acetylase system isolated from brain tissue and is destroyed by cholinesterase^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In rats, the infusion of 2 mg (±)-Acetylcarnitine chloride decreases blood flow through the hind limb vasculature 50%. (±)-Acetylcarnitine chloride also potentiates the inhibitory effect of adrenaline on the isolated rabbit duodenum^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

239.70

Formula

C₉H₁₈ClNO₄

CAS No.

2504-11-2

Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)CC(OC(C)=O)CC(O)=O.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (417.19 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.1719 mL	20.8594 mL	41.7188 mL
5 mM	0.8344 mL	4.1719 mL	8.3438 mL
10 mM	0.4172 mL	2.0859 mL	4.1719 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.60%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. R A Chalmers, et al. Urinary excretion of l-carnitine and acylcarnitines by patients with disorders of organic acid metabolism: evidence for secondary insufficiency of l-carnitine. Pediatr Res. 1984 Dec;18(12):1325-8. [Content Brief]

[2]. R L Sass, et al. Acetylcarnitine: on the relationship between structure and function. Biochem Biophys Res Commun. 1973 Dec 10;55(3):736-42. [Content Brief]

[3]. R T Louis-Ferdinand, et al. Flow decrease through rat hind limb vasculature by (plus or minus)-carnitine, (plus or minus)-acetylcarnitine and (plus or minss)-chloroacetylcarnitine chlorides. J Pharm Pharmacol. 1970 Sep;22(9):704-5. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.1719 mL	20.8594 mL	41.7188 mL	104.2970 mL
	5 mM	0.8344 mL	4.1719 mL	8.3438 mL	20.8594 mL
	10 mM	0.4172 mL	2.0859 mL	4.1719 mL	10.4297 mL
	15 mM	0.2781 mL	1.3906 mL	2.7813 mL	6.9531 mL
	20 mM	0.2086 mL	1.0430 mL	2.0859 mL	5.2149 mL
	25 mM	0.1669 mL	0.8344 mL	1.6688 mL	4.1719 mL
	30 mM	0.1391 mL	0.6953 mL	1.3906 mL	3.4766 mL
	40 mM	0.1043 mL	0.5215 mL	1.0430 mL	2.6074 mL
	50 mM	0.0834 mL	0.4172 mL	0.8344 mL	2.0859 mL
	60 mM	0.0695 mL	0.3477 mL	0.6953 mL	1.7383 mL
	80 mM	0.0521 mL	0.2607 mL	0.5215 mL	1.3037 mL
	100 mM	0.0417 mL	0.2086 mL	0.4172 mL	1.0430 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

(±)-Acetylcarnitine chloride Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-Acetylcarnitine2504-11-2Acetyl dl-carnitineCholinesterase (ChE)cholinergiclipidmetabolismintermediatesInhibitorinhibitorinhibit

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