2. Cell Cycle/DNA Damage
  3. RAD51
  4. RAD51-IN-5

RAD51-IN-5 is a potent inhibitor of RAD51. RAD51 is a eukaryote gene. RAD51-IN-5 has the potential for the research of conditions involving mitochondrial defects (extracted from patent WO2021164746A1, compound 3).

For research use only. We do not sell to patients.

RAD51-IN-5 Chemical Structure

RAD51-IN-5 Chemical Structure

CAS No. : 2690367-19-0

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Based on 1 publication(s) in Google Scholar

RAD51-IN-5 Related Antibodies

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Description

RAD51-IN-5 is a potent inhibitor of RAD51. RAD51 is a eukaryote gene. RAD51-IN-5 has the potential for the research of conditions involving mitochondrial defects (extracted from patent WO2021164746A1, compound 3)[1].

Molecular Weight

550.73

Formula

C26H38N4O5S2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)S(=N)(C1=C(C2=CN=C([C@@]3([H])CC[C@@H](CC3)NC(OC(C)C)=O)S2)C=CC(NC(OC(C)C)=O)=C1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (181.58 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8158 mL 9.0789 mL 18.1577 mL
5 mM 0.3632 mL 1.8158 mL 3.6315 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.87%

COA (247 KB) HNMR (281 KB) LCMS (266 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8158 mL 9.0789 mL 18.1577 mL 45.3943 mL
5 mM 0.3632 mL 1.8158 mL 3.6315 mL 9.0789 mL
10 mM 0.1816 mL 0.9079 mL 1.8158 mL 4.5394 mL
15 mM 0.1211 mL 0.6053 mL 1.2105 mL 3.0263 mL
20 mM 0.0908 mL 0.4539 mL 0.9079 mL 2.2697 mL
25 mM 0.0726 mL 0.3632 mL 0.7263 mL 1.8158 mL
30 mM 0.0605 mL 0.3026 mL 0.6053 mL 1.5131 mL
40 mM 0.0454 mL 0.2270 mL 0.4539 mL 1.1349 mL
50 mM 0.0363 mL 0.1816 mL 0.3632 mL 0.9079 mL
60 mM 0.0303 mL 0.1513 mL 0.3026 mL 0.7566 mL
80 mM 0.0227 mL 0.1135 mL 0.2270 mL 0.5674 mL
100 mM 0.0182 mL 0.0908 mL 0.1816 mL 0.4539 mL
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RAD51-IN-5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RAD51-IN-52690367-19-0RAD51eukaryote genemitochondrial defectsInhibitorinhibitorinhibit

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