C1s-A subcomponent Protein, Mouse (HEK293, His)

C1s-A subcomponent protein, a serine protease, is pivotal in the classical complement system pathway. Partnering with C1q and C1r, it forms C1, initiating complement activation. Activated by C1r, C1s can subsequently trigger downstream components C2 and C4, influencing the complement system cascade. C1s-A subcomponent Protein, Mouse (HEK293, His) is the recombinant mouse-derived C1s-A subcomponent protein, expressed by HEK293 , with C-His labeled tag.

C1s-A subcomponent protein is a serine protease that plays a crucial role in the classical pathway of the complement system. It associates with C1q and C1r to form C1, the initiating component of this pathway. Upon activation by C1r, C1s becomes capable of activating downstream components C2 and C4, contributing to the cascade of events in the complement system.

Biological activity has been tested in vitro.

Mouse

HEK293

C-His

Q8CG14 (E16-D688)

50908  [NCBI]

Approximately 76.6 kDa

Greater than 85% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.