Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His)

Carboxyester lipase/CEL protein plays a crucial role in cellular processes as it catalyzes the hydrolysis of a variety of substrates, including cholesterol esters, phospholipids, lysophospholipids, diacylglycerols and triacylglycerols, and lipids of hydroxy fatty acids acid ester. FAHF). Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is the recombinant mouse-derived Carboxyl Ester Lipase/CEL protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Carboxyl Ester Lipase/CEL Protein, Mouse (sf9, His) is 534 a.a., with molecular weight of ~133.9 & 59.1 kDa, respectively.

Carboxyl Ester Lipase (CEL) is an enzyme that catalyzes the hydrolysis of a diverse range of substrates, including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). CEL exhibits a preference for FAHFAs with the ester bond positioned further away from the carboxylate group, and it hydrolyzes unsaturated FAHFAs more rapidly than saturated ones. This enzymatic activity is essential for the complete digestion of dietary lipids in the gastrointestinal tract and facilitates the absorption of fat-soluble vitamins. CEL's role in lipid metabolism underscores its significance in the overall process of nutrient absorption and highlights its importance in maintaining lipid homeostasis.

Mouse

Sf9 insect cells

C-His

Q64285 (M1-L534)

12613  [NCBI]

Approximately 133.9&59.1 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.