DLK-1 Protein, Cynomolgus (HEK293, His)

DLK-1, also known as pre adipokine, is a transmembrane-secreted protein with an epidermal growth factor (EGF) -like repeat sequence. DLK-1 regulates the growth of pioneer axons by controlling Wnt signaling. DLK-1 is a cell surface protein expressed in many cancers, including hepatocellular carcinoma, and maybe a potential target for monoclonal antibodies to treat cancer. DLK-1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DLK-1 protein, expressed by HEK293 , with C-His labeled tag.

DLK-1, also known as pre adipokine, is a transmembrane-secreted protein with an epidermal growth factor (EGF) -like repeat sequence. DLK-1 is a member of the conserved MAPKKK double leucine zipper kinases (DLKs) that play a role in synaptic formation, axon regeneration and degeneration. DLK-1 regulates the growth of pioneer axons by controlling Wnt signaling. DLK-1 is a cell surface protein expressed in many cancers, including hepatocellular carcinoma, and maybe a potential target for monoclonal antibodies to treat cancer^[1][2][3].

Cynomolgus

HEK293

C-His

XP_005562275.1 (A24-C306)

102120804  [NCBI]

42-52 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.