GLO2/Glyoxalase II Protein, Human (GST)

GLO2, or Glyoxalase II Protein, serves as a thiolesterase, playing a crucial role in catalyzing the hydrolysis of S-D-lactoyl-glutathione. This activity generates glutathione and D-lactic acid, emphasizing GLO2's significance in cellular metabolism. The enzyme contributes to regulating glutathione levels and the conversion of substrates within cellular pathways. GLO2/Glyoxalase II Protein, Human (GST) is the recombinant human-derived GLO2/Glyoxalase II protein, expressed by E. coli , with N-GST labeled tag.

GLO2, also known as Glyoxalase II, functions as a thiolesterase, playing a pivotal role in catalyzing the hydrolysis of S-D-lactoyl-glutathione. This enzymatic activity results in the formation of glutathione and D-lactic acid. The specific role of GLO2 in this process underscores its importance in the cellular metabolism of S-D-lactoyl-glutathione, contributing to the regulation of glutathione levels and the conversion of substrates involved in cellular pathways.

Human

E. coli

N-GST

Q16775-1 (K50-D308)

3029  [NCBI]

KVEVLPALTDNYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLESGLKVYGGDDRIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEPGNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAVRREKDQFKMPRD

Approximately 55.7 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.