LEDGF p52 Protein, Human

LEDGF p52 protein is involved in essential functions, such as DNA-binding and chromatin binding activity. It positively regulates transcription and plays a role in mRNA 5'-splice site recognition. The protein is located in heterochromatin, the nuclear periphery, and the nucleoplasm. It is ubiquitously expressed in various tissues, including the brain (RPKM 41.2), ovary (RPKM 33.4), and 24 other tissues. LEDGF p52 Protein, Human is the recombinant human-derived LEDGF p52 protein, expressed by E. coli , with tag free.

The LEDGF p52 protein is involved in various essential functions, including DNA-binding transcription factor binding activity, chromatin binding activity, and transcription coactivator activity. It plays a role in mRNA 5'-splice site recognition and positively regulates transcription by RNA polymerase II. The protein is located in heterochromatin, the nuclear periphery, and the nucleoplasm. It exhibits ubiquitous expression in multiple tissues, including the brain (RPKM 41.2), ovary (RPKM 33.4), and 24 other tissues.

Human

E. coli

Tag Free

O75475-2/NP_066967 (M1-Q333)

11168  [NCBI]

MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEHQTTCNLQ

Approximately 51 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.